Items by Watts, Dr Andrew
|Up a level|
Hader, S. and Watts, A., 2013. The synthesis of a series of deoxygenated 2,3-difluoro-N-acetylneuraminic acid derivatives as potential sialidase inhibitors. Carbohydrate Research, 374, pp. 23-28.
Lasheen, D. S., Ismail, M. A. H., Abou El Ella, D. A., Ismail, N. S. M., Eid, S., Vleck, S., Glenn, J. S., Watts, A. G. and Abouzid, K. A. M., 2013. Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activity. Bioorganic and Medicinal Chemistry, 21 (10), pp. 2742-2755.
Watts, Andrew, 2012. Materials and methods relating to glycosylation. A61K47/48-EP2442831 (A2), 25 April 2012.
Watts, Andrew, 2012. Functionalising reagents and their uses. CN102317305 (A), 11 January 2012.
Watts, Andrew, 2011. Thiol-Functionalising Reagents and Their Uses. C07K1/13-EP2373675 (A2), 12 October 2011.
Telford, J. C., Yeung, J. H. F., Xu, G. G., Kiefel, M. J., Watts, A., Hader, S., Chan, J., Bennet, A. J., Moore, M. M. and Taylor, G. L., 2011. The Aspergillus fumigatus Sialidase Is a 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid Hydrolase (KDNase): Structural and mechanistic insights. Journal of Biological Chemistry, 286 (12), pp. 10783-10792.
Watts, Andrew, 2010. Materials and Methods Relating to Glycosylation. A61K47/48-CA2768155 (A1), 23 December 2010.
Watts, Andrew, 2010. Compounds for Treating Viral Infections. C07H7/02-WO2010029302 (A2), 18 March 2010.
Resende, R., Glover, C. and Watts, A. G., 2009. Palladium-catalysed allylic amination for the direct synthesis of epi-4-alkylamino-N-acetylneuraminic acid derivatives. Tetrahedron Letters, 50 (28), pp. 4009-4011.
Mackenzie, Amanda, 2009. Detection and Functionalisation of S-Nitrosylated Polypeptides. G01N33/68-WO2009024791 (A1), 26 February 2009.
Hewinson, J., Moore, S. F., Glover, C., Watts, A. and Mackenzie, A. B., 2008. A key role for redox signaling in rapid P2X7 receptor-induced IL-1 β processing in human monocytes. The Journal of Immunology, 180 (12), pp. 8410-8420.
Newstead, S. L., Potter, J. A., Wilson, J. C., Xu, G., Chien, C. -H., Watts, A. G., Withers, S. G. and Taylor, G. L., 2008. The structure of Clostridium perfringens NanI sialidase and its catalytic intermediates. Journal of Biological Chemistry, 283 (14), pp. 9080-9088.
Damager, I., Buchini, S., Amaya, M. F., Buschiazzo, A., Alzari, P., Frasch, A. C., Watts, A. G. and Withers, S. G., 2008. Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis. Biochemistry, 47 (11), pp. 3507-3512.
Müller, A., Severi, E., Mulligan, C., Watts, A. G., Kelly, D. J., Wilson, K. S., Wilkinson, A. J. and Thomas, G. H., 2006. Conservation of structure and mechanism in primary and secondary transporters exemplified by SiaP, a sialic acid-binding virulence factor from Haemophilus Influenzae. Journal of Biological Chemistry, 281 (31), pp. 22212-22222.
Watts, A. G., Oppezzo, P., Withers, S. G., Alzari, P. M. and Buschiazzo, A., 2006. Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on trypanosoma rangeli sialidase. Journal of Biological Chemistry, 281 (7), pp. 4149-4155.
Lairson, L. L., Watts, A. G., Wakarchuk, W. W. and Withers, S. G., 2006. Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis. Nature Chemical Biology, 2 (12), pp. 724-728.
McDonough, M. J., Stick, R. V., Tilbrook, D. M. G. and Watts, A. G., 2004. An investigation into the synthesis of some molecules related to methyl acarviosin. Australian Journal of Chemistry, 57 (3), pp. 233-241.
Watts, A. G. and Withers, S. G., 2004. Glycosynthase-catalysed formation of modified polysaccharide microstructures. Biochemical Journal, 380, e1-e2.
Stick, R. V., Stubbs, K. A. and Watts, A. G., 2004. Modifying the regioselectivity of glycosynthase reactions through changes in the acceptor. Australian Journal of Chemistry, 57, pp. 779-786.
Chiu, C. P. C., Watts, A. G., Lairson, L. L., Gilbert, M., Lim, D., Wakarchuk, W. W., Withers, S. G. and Strynadka, N. C. J., 2004. Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog. Nature Structural and Molecular Biology, 11 (2), pp. 163-170.
Amaya, M. F., Watts, A. G., Damager, I., Wehenkel, A., Nguyen, T., Buschiazzo, A., Paris, G., Frasch, A. C., Withers, S. G. and Alzari, P. M., 2004. Structural insights into the catalytic mechanism of trypanosoma cruzi trans-sialidase. Structure, 12 (5), pp. 775-784.
Skelton, B. W., Stick, R. V., Stubbs, K. A., Watts, A. G. and White, A. H., 2004. The fluorination (at C5) of some derivatives of D-glucose. Australian Journal of Chemistry, 57, pp. 345-353.
Watts, A. G. and Withers, S. G., 2004. The synthesis of some mechanistic probes for sialic acid processing enzymes and the labeling of a sialidase from Trypanosoma rangeli. Canadian Journal of Chemistry, 82, pp. 1581-1588.
Watts, A. G., Damager, I., Amaya, M. L., Buschiazzo, A., Alzari, P. M., Frasch, A. C. and Withers, S. G., 2003. Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile. Journal of the American Chemical Society, 125 (25), pp. 7532-7533.
Stick, R. V. and Watts, A. G., 2002. A direct synthesis of 2-deoxy-2-fluoro-α-D-[6- 3 H]glucopyranosyl uridine-5'-diphosphate. Australian Journal of Chemistry, 55, pp. 327-329.
Stick, R. V., Stubbs, K. A., Tilbrook, D. M. G. and Watts, A. G., 2002. A new catalyst for the reductive elimination of acylated glycosyl bromides to form glycals. Australian Journal of Chemistry, 55, pp. 83-85.
Stick, R. V. and Watts, A. G., 2002. The chameleon of retaining glycoside hydrolases and retaining glycosol transferases: the catalytic nucleophile. Chemical Monthly, 133, pp. 541-554.