Items by Thiyagarajan, Nethaji

Thiyagarajan, N. and Acharya, K.R., 2013. Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule. FEBS Open Bio, 3, pp. 65-70.

Thiyagarajan, N., Ferguson, R., Subramanian, V. and Acharya, K. R., 2012. Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons. Nature Communications, 3, 1121.

Thiyagarajan, N., Pham, T. T. K., Stinson, B., Sundriyal, A., Tumbale, P., Lizotte-waniewski, M., Brew, K. and Acharya, K. R., 2012. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Scientific Reports, 2, 940.

Kirby, J. M., Thiyagarajan, N., Roberts, A. K., Shone, C. C. and Acharya, K. R., 2011. Expression, purification, crystallization and preliminary crystallographic analysis of a putative Clostridium difficile surface protein Cwp19. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 67 (7), pp. 762-767.

Thiyagarajan, N., Smith, B. D., Raines, R. T. and Acharya, K. R., 2011. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. FEBS Journal, 278 (3), pp. 541-549.

Leese, M. P., Jourdan, F., Kimberley, M. R., Cozier, G. E., Thiyagarajan, N., Stengel, C., Regis-Lydi, S., Foster, P. A., Newman, S. P., Acharya, K. R., Ferrandis, E., Purohit, A., Reed, M. J. and Potter, B. V. L., 2010. Chimeric microtubule disruptors. Chemical Communications, 46 (17), pp. 2907-2909.

Cozier, G. E., Leese, M. P., Lloyd, M. D., Baker, M. D., Thiyagarajan, N., Acharya, K. R. and Potter, B. V. L., 2010. Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors. Biochemistry, 49 (16), pp. 3464-3476.

Mitsiki, E., Papageorgiou, A. C., Iyer, S., Thiyagarajan, N., Prior, S. H., Sleep, D., Finnis, C. and Acharya, K. R., 2009. Structures of native human thymidine phosphorylase and in complex with 5-iodouracil. Biochemical and Biophysical Research Communications, 386 (4), pp. 666-670.

Masuyer, G., Thiyagarajan, N., James, P. L., Marks, P. M. H., Chaddock, J. A. and Acharya, K. R., 2009. Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A. Biochemical and Biophysical Research Communications, 381 (1), pp. 50-53.

Ulrich, M., Petre, A., Youhnovski, N., Promm, F., Schirle, M., Schumm, M., Pero, R. S., Doyle, A., Checkel, J., Kita, H., Thiyagarajan, N., Acharya, K. R., Schmid-Grendelmeier, P., Simon, H. U., Schwarz, H., Tsutsui, M., Shimokawa, H., Bellon, G., Lee, J. J., Przybylski, M. and Doring, G., 2008. Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. Journal of Biological Chemistry, 283 (42), pp. 28629-28640.

Tumbale, P., Jamaluddin, H., Thiyagarajan, N., Acharya, K. R. and Brew, K., 2008. Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of α-1,3-galactosyltransferase. Glycobiology, 18 (12), pp. 1036-1043.

Tumbale, P., Jamaluddin, H., Thiyagarajan, N., Brew, K. and Acharya, K. R., 2008. Structural Basis of UDP-galactose Binding by α-1,3-Galactosyltransferase (α3GT): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47 (33), pp. 8711-8718.

Crabtree, B., Thiyagarajan, N., Prior, S. H., Wilson, P., Iyer, S., Ferns, T., Shapiro, R., Brew, K., Subramanian, V. and Acharya, K. R., 2007. Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry, 46 (42), pp. 11810-11818.

Jenkins, C. L., Thiyagarajan, N., Sweeney, R. Y., Guy, M. P., Kelemen, B. R., Acharya, K. R. and Raines, R. T., 2005. Binding of non-natural 3 '-nucleotides to ribonuclease A. FEBS Journal, 272 (3), pp. 744-755.

Lloyd, M. D., Thiyagarajan, N., Ho, Y. T., Woo, L. W. L., Sutcliffe, O. B., Purohit, A., Reed, M. J., Acharya, K. R. and Potter, B. V. L., 2005. First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors. Biochemistry, 44 (18), pp. 6858-6866.

Turton, K., Natesh, R., Thiyagarajan, N., Chaddock, J. A. and Acharya, K. R., 2004. Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose. Glycobiology, 14 (10), pp. 923-929.