Research

Items by Guy, Richard

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Number of items: 167.

Book/s

Guy, R. H. and Hadgraft, J., 2003. Transdermal drug delivery. New York: Marcel Dekker.

Testa, B., van der Waterbeemd, H., Folkers, G., Guy, R. H. and van de Waterbeemd, H., 2001. Pharmacokinetic optimization in drug research. Lausanne: Wiley-VCH.

Book Sections

Guy, R. H., 2010. Transdermal drug delivery. In: Schafer-Korting, M., ed. Drug Delivery. Vol. 197. 197 ed. Springer, pp. 399-410. (Handbook of Experimental Pharmacology)

Mudry, B., Guy, R. H. and Delgado-Charro, M. B., 2006. Iontophoresis in transdermal delivery. In: Touitou, E. and Barry, B. W., eds. Enhancement in drug delivery. Boco Raton: CRC Press, pp. 279-302.

Abla, N., Raik, A., Guy, R. H. and Kalia, Y. N., 2005. Iontophoresis: clinical applications and future challenges. In: Smith, E. W. and Maibach, H. I., eds. Percutaneous Penetration Enhancers, 2nd ed. Vol. 2nd Edition. Boca Raton, Florida: CRC Press, pp. 177-219.

Bunge, A. L., Touraille, G. D., Marty, J. P. and Guy, R. H., 2005. Modeling dermal absorption from soils and powders using stratum corneum tape-stripping in vivo. In: Riviere, J. E., ed. Dermal Absorption Models in Toxicology and Pharmacology. Boca Raton, Florida: CRC Press, pp. 191-212.

Guy, R. H., 2003. 'Minimally invasive' technologies for transdermal delivery and clinical chemistry. In: Challenge in Drug Delivery for the New Millenium. Bulletin Technique Gattefossé 96. Vol. 96. , pp. 47-61. (Bulletin Technique Gattefossé)

Hadgraft, J. and Guy, R. H., 2003. Feasibility assessment in topical and transdermal delivery: mathematical models and in vitro studies. In: Guy, R. H. and Hadgraft, J., eds. Transdermal Drug Delivery, 2nd ed. Vol. 2nd Edition, Revised and Expanded. New York: Marcel Dekker, pp. 1-23.

Delgado-Charro, M. B. and Guy, R. H., 2003. Iontophoresis: applications in drug delivery and noninvasive monitoring. In: Guy, R. H. and Hadgraft, J., eds. Transdermal Drug Delivery Systems, 2nd ed. Vol. 2nd Edition, Revised and Expanded. New York: Marcel Dekker, pp. 199-225.

Sekkat, N. and Guy, R. H., 2001. Biological models to study skin permeation. In: Testa, B., van der Waterbeemd, G., Folkers, G. and Guy, R. H., eds. Pharmacokinetic optimization in drug research: biological, physicochemical and computational strategies. Lausanne: Wiley-VCH, pp. 155-172.

Marro, D., Delgado-Charro, M. B. and Guy, R. H., 2001. Peptides and proteins - transdermal absorption. In: Swarbrick, J. and Boylan, J. C., eds. Encyclopaedia of Pharmaceutical Technology, 2nd ed. Vol. 2nd Edition. New York: Marcel Dekker, pp. 2125-2140.

Delgado-Charro, M. B. and Guy, R. H., 2001. Transdermal drug delivery. In: Hillery, A. M., Lloyd, A. W. and Swarbrick, J., eds. Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists. London: Harwood Academic Publishers, pp. 207-236.

Articles

Wiedersberg, S. and Guy, R. H., 2014. Transdermal drug delivery : 30 + years of war and still fighting! Journal of Controlled Release, 190, pp. 150-156.

Yang, Q. and Guy, R.H., 2014. Forthcoming. Characterisation of Skin Barrier Function Using Bioengineering and Biophysical Techniques. Pharmaceutical Research

Cordery, S. F., Taverner, A., Ridzwan, I. E., Guy, R. H., Delgado-Charro, M. B., Husbands, S. M. and Bailey, C. P., 2014. A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm. Addiction Biology, 19 (4), pp. 575-586.

Delgado-Charro, M. B. and Guy, R. H., 2014. Effective use of transdermal drug delivery in children. Advanced Drug Delivery Reviews, 73, pp. 63-82.

Thitilertdecha, P., Guy, R.H. and Rowan, M.G., 2014. Characterisation of polyphenolic compounds in Clerodendrum petasites S. Moore and their potential for topical delivery through the skin. Journal of Ethnopharmacology, 154 (2), pp. 400-407.

Guy, R.H., Kuma, H. and Nakanishi, M., 2014. Serious photocontact dermatitis induced by topical ketoprofen depends on the formulation. European Journal of Dermatology, 24 (3), pp. 365-371.

Belsey, N. A., Garrett, N. L., Contreras-Rojas, L. R., Pickup-Gerlaugh, A. J., Price, G. J., Moger, J. and Guy, R. H., 2014. Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies. Journal of Controlled Release, 174 (28), pp. 37-42.

Güngör, S., Delgado-Charro, M. B., Masini-Etévé, V., Potts, R. O. and Guy, R. H., 2013. Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs) : Comparison with experimental results. Journal of Controlled Release, 172 (3), pp. 601-606.

Ridd, M., Guy, R., Ball, N., Roberts, A. and Williams, H., 2013. Products in "Bounty bags" potentially harm newborn skin. BMJ, 346 (7913), f3895.

Benzeval, I., Bowen, C. R., Guy, R. H. and Delgado-Charro, M. B., 2013. Effects of iontophoresis, hydration, and permeation enhancers on human nail plate: Infrared and impedance spectroscopy assessment. Pharmaceutical Research, 30 (6), pp. 1652-1662.

Beard, J. D., Guy, R. H. and Gordeev, S. N., 2013. Mechanical tomography of human corneocytes with a nanoneedle. Journal Of Investigative Dermatology, 133 (6), pp. 1565-1571.

Gelfuso, G. M., Gratieri, T., Delgado-Charro, M. B., Guy, R. H. and Vianna Lopez, R. F., 2013. Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia. Journal of Pharmaceutical Sciences, 102 (5), pp. 1488-1494.

Russell, L.M. and Guy, R.H., 2012. Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies : Proof-of-concept with acyclovir formulations. Pharmaceutical Research, 29 (12), pp. 3362-3372.

Djabri, A., Guy, R. H. and Delgado-Charro, M. B., 2012. Transdermal iontophoresis of ranitidine: An opportunity in paediatric drug therapy. International Journal of Pharmaceutics, 435 (1), pp. 27-32.

Mohammed, D., Yang, Q., Guy, R.H., Matts, P.J., Hadgraft, J. and Lane, M.E., 2012. Comparison of gravimetric and spectroscopic approaches to quantify stratum corneum removed by tape-stripping. European Journal of Pharmaceutics and Biopharmaceutics, 82 (1), pp. 171-174.

Russell, L. M. and Guy, R. H., 2012. Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies. Pharmaceutical Research, 29 (9), pp. 2389-2397.

Campbell, C. S. J., Contreras-Rojas, L. R., Delgado-Charro, B. and Guy, R. H., 2012. Objective assessment of nanoparticle disposition in mammalian skin after topical exposure. Journal of Controlled Release, 162 (1), pp. 201-207.

Djabri, A., Guy, R. H. and Delgado-Charro, M. B., 2012. Passive and iontophoretic transdermal delivery of phenobarbital: implications in paediatric therapy. International Journal of Pharmaceutics, 435 (1), pp. 76-82.

Mitragotri, S., Anissimov, Y. G., Bunge, A. L., Frasch, H. F., Guy, R. H., Hadgraft, J., Kasting, G. B., Lane, M. E. and Roberts, M. S., 2011. Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), pp. 115-129.

Saar, B. G., Contreras-Rojas, L. R., Xie, X. S. and Guy, R. H., 2011. Imaging drug delivery to skin with stimulated Raman scattering microscopy. Molecular Pharmaceutics, 8 (3), pp. 969-975.

Belsey, N. A., Cordery, S. F., Bunge, A. L. and Guy, R. H., 2011. Assessment of dermal exposure to pesticide residues during re-entry. Environmental Science & Technology, 45 (10), pp. 4609-4615.

Guy, R. H. and Szoka, F. C., 2011. Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG): implications for PEG-induced biomembrane fusion. Physical Chemistry Chemical Physics, 13 (12), pp. 5346-5352.

Beard, J. D., Gordeev, S. N. and Guy, R. H., 2011. AFM nanotools for surgery of biological Cells. Journal of Physics: Conference Series, 286 (1), 012003.

Watkinson, R. M., Guy, R. H., Oliveira, G., Hadgraft, J. and Lane, M. E., 2011. Optimisation of Cosolvent Concentration for Topical Drug Delivery III - Influence of Lipophilic Vehicles on Ibuprofen Permeation. Skin Pharmacology and Physiology, 24 (1), pp. 22-26.

Taverner, A., Cordery, S., Husbands, S. M., Guy, R. H., Delgado-Charro, B. M. and Bailey, C. P., 2011. Transdermal delivery of a buprenorphine/naltrexone combination for the treatment of polydrug abuse. Pharmacological Reports, 63 (1), p. 257.

Yang, Q., Cordery, S. and Guy, R. H., 2010. Application of biophysics and bioengineering to the assessment of barrier function. Journal of Pharmacy and Pharmacology, 62 (10), pp. 1249-1250.

Güngör, S., Delgado-Charro, M. B., Ruiz-Perez, B., Schubert, W., Isom, P., Moslem, P., Patane, M. A. and Guy, R. H., 2010. Trans-scleral iontophoretic delivery of low molecular weight therapeutics. Journal of Controlled Release, 147 (2), pp. 225-231.

Sylvestre, J. P., Bouissou, C., Guy, R. H. and Delgado-Charro, M. B., 2010. Extraction and quantification of amino acids in human stratum corneum in vivo. British Journal of Dermatology, 163 (3), pp. 458-465.

Hathout, R. M., Woodman, T. J., Mansour, S., Mortada, N. D., Geneidi, A. S. and Guy, R. H., 2010. Microemulsion formulations for the transdermal delivery of testosterone. European Journal of Pharmaceutical Sciences, 40 (3), pp. 188-196.

Wu, X., Landfester, K., Musyanovych, A. and Guy, R. H., 2010. Disposition of charged nanoparticles after their topical application to the skin. Skin Pharmacology and Physiology, 23 (3), pp. 117-123.

Tsang, M. and Guy, R. H., 2010. Effect of Aqueous Cream BP on human stratum corneum in-vivo. British Journal of Dermatology, 163 (5), pp. 954-958.

Thitilertdecha, P., Akkarasereenont, P., Laohapand, T., Rowan, M. G. and Guy, R. H., 2010. Formulation optimisation for the topical delivery of active agents in traditional medicines. Journal of Pharmacy and Pharmacology, 62 (10), pp. 1272-1273.

Guy, R. H., 2010. Predicting the rate and extent of fragrance chemical absorption into and through the skin. Chemical Research in Toxicology, 23 (5), pp. 864-870.

Hathout, R. M., Mansour, S., Mortada, N. D., Geneidi, A. S. and Guy, R. H., 2010. Uptake of microemulsion components into the stratum corneum and their molecular effects on skin barrier function. Molecular Pharmaceutics, 7 (4), pp. 1266-1273.

Bouissou, C. C., Sylvestre, J.-P., Guy, R. H. and Delgado-Charro, M. B., 2009. Reverse iontophoresis of amino acids: identification and separation of stratum corneum and subdermal sources in vitro. Pharmaceutical Research, 26 (12), pp. 2630-2638.

Wu, X. and Guy, R. H., 2009. Applications of nanoparticles in topical drug delivery and in cosmetics. Journal of Drug Delivery Science and Technology, 19 (6), pp. 371-384.

Wu, X., Price, G. J. and Guy, R. H., 2009. Disposition of nanoparticles and an associated lipophilic permeant following topical application to the skin. Molecular Pharmaceutics, 6 (5), pp. 1441-1448.

Wu, X., Griffin, P., Price, G. J. and Guy, R. H., 2009. Preparation and in vitro evaluation of topical formulations based on polystyrene-poly-2-hydroxyl methacrylate nanoparticles. Molecular Pharmaceutics, 6 (5), pp. 1449-1456.

Wu, X., Biatry, B., Cazeneuve, C. and Guy, R. H., 2009. Drug delivery to the skin From sub-micron polymeric particle formulations: Influence of particle size and polymer hydrophobicity. Pharmaceutical Research, 26 (8), pp. 1995-2001.

Cork, M. J., Danby, S. G., Vasilopoulos, Y., Hadgraft, J., Lane, M. E., Moustafa, M., Guy, R. H., Macgowan, A. L., Tazi-Ahnini, R. and Ward, S. J., 2009. Epidermal barrier dysfunction in atopic dermatitis. Journal Of Investigative Dermatology, 129 (8), pp. 1892-1908.

Nicoli, S., Bunge, A. L., Delgado-Charro, M. B. and Guy, R. H., 2009. Dermatopharmacokinetics: factors influencing drug clearance from the stratum corneum. Pharmaceutical Research, 26 (4), pp. 865-871.

Wiedersberg, S., Leopold, C. S. and Guy, R. H., 2009. Dermatopharmacokinetics of betamethasone 17-valerate: Influence of formulation viscosity and skin surface cleaning procedure. European Journal of Pharmaceutics and Biopharmaceutics, 71 (2), pp. 362-366.

N’Dri-Stempfer, B., Navidi, W. C., Guy, R. H. and Bunge, A. L., 2009. Improved bioequivalence assessment of topical dermatological drug products using dermatopharmacokinetics. Pharmaceutical Research, 26 (2), pp. 316-328.

Watkinson, R. M., Herkenne, C., Guy, R. H., Hadgraft, J., Oliveira, G. and Lane, M. E., 2009. Influence of ethanol on the solubility, ionization and permeation characteristics of ibuprofen in silicone and human skin. Skin Pharmacology and Physiology, 22 (1), pp. 15-21.

Grégoire, S., Ribaud, C., Benech, F., Meunier, J. R., Garrigues-Mazert, A. and Guy, R. H., 2009. Prediction of chemical absorption into and through the skin from cosmetic and dermatological formulations. British Journal of Dermatology, 160 (1), pp. 80-91.

Yow, H. N., Wu, X., Routh, A. F. and Guy, R. H., 2009. Dye diffusion from microcapsules with different shell thickness into mammalian skin. European Journal of Pharmaceutics and Biopharmaceutics, 72 (1), pp. 62-68.

Wiedersberg, S., Leopold, C. S. and Guy, R. H., 2009. Effects of Various Vehicles on Skin Hydration in vivo. Skin Pharmacology and Physiology, 22 (3), pp. 128-130.

Sieg, A., Jeanneret, F., Fathi, M., Hochstrasser, D., Rudaz, S., Veuthey, J. L., Guy, R. H. and Delgado-Charro, M. B., 2009. Extraction of amino acids by reverse iontophoresis in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 72 (1), pp. 226-231.

Mehier-Humbert, S., Bettinger, T., Yan, F. and Guy, R. H., 2009. Influence of polymer adjuvants on the ultrasound-mediated transfection of cells in culture. European Journal of Pharmaceutics and Biopharmaceutics, 72 (3), pp. 567-573.

Russell, L. M. and Guy, R. H., 2009. Measurement and prediction of the rate and extent of drug delivery into and through the skin. Expert Opinion on Drug Delivery, 6 (4), pp. 355-369.

Watkinson, R. M., Guy, R. H., Hadgraft, J. and Lane, M. E., 2009. Optimisation of cosolvent concentration for topical drug delivery - II: Influence of propylene glycol on Ibuprofen permeation. Skin Pharmacology and Physiology, 22 (4), pp. 225-230.

Wiedersberg, S., Naik, A., Leopold, C. S. and Guy, R. H., 2009. Pharmacodynamics and dermatopharmacokinetics of betamethasone 17-valerate: assessment of topical bioavailability. British Journal of Dermatology, 160 (3), pp. 676-686.

Sylvestre, J., Diaz-Marin, C., Delgado-Charro, M. and Guy, R., 2008. Iontophoresis of dexamethasone phosphate: Competition with chloride ions. Journal of Controlled Release, 131 (1), pp. 41-46.

Sylvestre, J. -P., Guy, R. H. and Delgado-Charro, M. B., 2008. In vitro optimization of Dexamethasone Phosphate delivery by iontophoresis. Physical Therapy, 88 (10), pp. 1177-1185.

Dias, M., Naik, A., Guy, R. H., Hadgraft, J. and Lane, M. E., 2008. In vivo infrared spectroscopy studies of alkanol effects on human skin. European Journal of Pharmaceutics and Biopharmaceutics, 69 (3), pp. 1171-1175.

Wascotte, V., Rozet, E., Salvaterra, A., Hubert, P., Jadoul, M., Guy, R. H. and Préat, V., 2008. Non-invasive diagnosis and monitoring of chronic kidney disease by reverse iontophoresis of urea in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 69 (3), pp. 1077-1082.

N'Dri-Stempfer, B., Navidi, W. C., Guy, R. H. and Bunge, A. L., 2008. Optimizing metrics for the assessment of bioequivalence between topical drug products. Pharmaceutical Research, 25 (7), pp. 1621-1630.

Wiedersberg, S., Leopold, C. S. and Guy, R. H., 2008. Bioavailability and bioequivalence of topical glucocorticoids. European Journal of Pharmaceutics and Biopharmaceutics, 68 (3), pp. 453-466.

Trichard, L., Delgado-Charro, M. B., Guy, R. H., Fattal, E. and Bochot, A., 2008. Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug. Pharmaceutical Research, 25 (2), pp. 435-440.

Herkenne, C., Naik, A., Kalia, Y. N., Hadgraft, J. and Guy, R. H., 2008. Effect of propylene glycol on ibuprofen absorption into human skin in vivo. Journal of Pharmaceutical Sciences, 97 (1), pp. 185-197.

Herkenne, C., Alberti, I., Naik, A., Kalia, Y. N., Mathy, F. X., Préat, V. and Guy, R. H., 2008. In vivo methods for the assessment of topical drug bioavailability. Pharmaceutical Research, 25 (1), pp. 87-103.

Sieg, A., Jeanneret, F., Fathi, M., Hochstrasser, D., Rudaz, S., Veuthey, J. L., Guy, R. H. and Delgado-Charro, M. B., 2008. Extraction of amino acids by reverse iontophoresis: Simulation of therapeutic monitoring in vitro. European Journal of Pharmaceutics and Biopharmaceutics, 70 (3), pp. 908-913.

Nixon, S., Sieg, A., Delgado-Charro, M. and Guy, R., 2007. Reverse iontophoresis of L-lactate: in vitro and in vivo studies. Journal of Pharmaceutical Sciences, 96 (12), pp. 3457-3465.

Kroes, R., Renwick, A. G., Feron, V., Galli, C. L., Gibney, M., Greim, H., Guy, R. H., Lhugeonot, J. C. and van de Sandt, J. J. M., 2007. Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients. Food and Chemical Toxicology, 45 (12), pp. 2533-2562.

Wascotte, V., Caspers, P., de Sterke, J., Jadoul, M., Guy, R. H. and Préat, V., 2007. Assessment of the "Skin Reservoir" of urea by Confocal Raman Microspectroscopy and reverse iontophoresis in vivo. Pharmaceutical Research, 24 (10), pp. 1897-1901.

Herkenne, C., Naik, A., Kalia, Y. N., Hadgraft, J. and Guy, R. H., 2007. Dermatopharmacokinetic prediction of topical drug bioavailability in vivo. Journal Of Investigative Dermatology, 127 (4), pp. 887-894.

Cork, M. J., Varghese, J., Hadcraft, J., Lane, M., Ferguson, A., Moustafa, M., Guy, R. H. and Ward, S., 2007. Differences in the effect of topical corticosteroids and calcineurin inhibitors on the skin barrier - Implications for therapy. Journal Of Investigative Dermatology, 127, S45-S45.

Diaz del Consuelo, I., Falson, F., Guy, R. H. and Jacques, Y., 2007. Ex vivo evaluation of bioadhesive films for buccal delivery of fentanyl. Journal of Controlled Release, 122 (2), pp. 135-140.

Herkenne, C., Naik, A., Kalia, Y. N., Hadgraft, J. and Guy, R. H., 2007. Ibuprofen transport into and through skin from topical formulations: in vitro - in vivo comparison. Journal Of Investigative Dermatology, 127 (1), pp. 135-142.

Leichtnam, M. L., Rolland, H., Wüthrich, P. and Guy, R. H., 2007. Impact of antinucleants on transdermal delivery of testosterone from a spray. Journal of Pharmaceutical Sciences, 96 (1), pp. 84-92.

Wascotte, V., Delgado-Charro, M. B., Rozet, E., Wallemacq, P., Hubert, P., Guy, R. H. and Préat, V., 2007. Monitoring of urea and potassium by reverse iontophoresis in vitro. Pharmaceutical Research, 24 (6), pp. 1131-1137.

Mudry, B., Carrupt, P. A., Guy, R. H. and Delgado-Charro, M. B., 2007. Quantitative structure-permeation relationship for iontophoretic transport across the skin. Journal of Controlled Release, 122 (2), pp. 165-172.

Djabri, A., Guy, R. H. and Delgado-Charro, M. B., 2007. Transdermal reverse lontophoresis of lohexol as a tool for minimally-invasive monitoring of renal function. Therapeutic Drug Monitoring, 29 (4), pp. 532-533.

Guy, R. H., 2007. Transdermal science and technology - an update. Drug Delivery System, 22 (4), pp. 442-449.

Mehier-Humbert, S., Yan, F., Frinking, P., Schneider, M., Guy, R. H. and Bettinger, T., 2007. Ultrasound-mediated gene delivery: influence of contrast agent on transfection. Bioconjugate Chemistry, 18, pp. 652-662.

Mudry, B., Guy, R. H. and Delgado-Charro, M. B., 2006. Electromigration of ions across the skin: determination and prediction of transport numbers. Journal of Pharmaceutical Sciences, 95 (3), pp. 561-569.

Leichtnam, M. L., Rolland, H., Wüthrich, P. and Guy, R. H., 2006. Enhancement of transdermal testosterone delivery by supersaturation. Journal of Pharmaceutical Sciences, 95 (11), pp. 2373-2379.

Leichtnam, M. L., Rolland, H., Wüthrich, P. and Guy, R. H., 2006. Formulation and evaluation of a testosterone transdermal spray. Journal of Pharmaceutical Sciences, 95 (8), pp. 1693-1702.

Leichtnam, M. L., Rolland, H., Wüthrich, P. and Guy, R. H., 2006. Identification of penetration enhancers for testosterone transdermal delivery from spray formulations. Journal of Controlled Release, 113, pp. 57-62.

Herkenne, C., Naik, A., Kalia, Y. N., Hadgraft, J. and Guy, R. H., 2006. Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man. Pharmaceutical Research, 23 (8), pp. 1850-1856.

Mudry, B., Guy, R. H. and Delgado-Charro, M. B., 2006. Prediction of iontophoretic transport across the skin. Journal of Controlled Release, 111, pp. 362-367.

Schuetz, Y. B., Carrupt, P. A., Naik, A., Guy, R. H. and Kalia, Y. N., 2006. Structure-permeation relationships for the non-invasive transdermal delivery of cationic peptides by iontophoresis. European Journal of Pharmaceutical Sciences, 29, pp. 53-59.

Leichtnam, M. L., Rolland, H., Wüthrich, P. and Guy, R. H., 2006. Testosterone hormone replacement therapy: state-of-the-art and emerging technologies. Pharmaceutical Research, 23 (6), pp. 1117-1132.

Abla, N., Naik, A., Guy, R. H. and Kalia, Y. N., 2006. Topical iontophoresis of valaciclovir hydrochloride improves cutaneous aciclovir delivery. Pharmaceutical Research, 23 (8), pp. 1842-1849.

Mudry, B., Guy, R. H. and Delgado-Charro, M. B., 2006. Transport numbers in transdermal iontophoresis. Biophysical Journal, 90, pp. 2822-2830.

Abla, N., Geiser, L., Mirgaldi, M., Naik, A., Veuthey, J. L., Guy, R. H. and Kalia, Y. N., 2005. Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility. Journal of Pharmaceutical Sciences, 94 (12), pp. 2667-2675.

Diaz del Consuelo, I., Pizzolato, G. P., Jacques, Y., Guy, R. H. and Falson, F., 2005. Comparison of the lipid composition of porcine buccal and esophageal permeability barriers. Archives of Oral Biology, 50, pp. 981-987.

Abla, N., Naik, A., Guy, R. H. and Kalia, Y. N., 2005. Contributions of electromigration and electroosmosis to peptide iontophoresis across intact and impaired skin. Journal of Controlled Release, 108, pp. 319-330.

Schuetz, Y. B., Naik, A., Guy, R. H. and Kalia, Y. N., 2005. Effect of amino acid sequence on transdermal iontophoretic peptide delivery. European Journal of Pharmaceutical Sciences, 26, pp. 429-437.

Abla, N., Naik, A., Guy, R. H. and Kalia, Y. N., 2005. Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis. Pharmaceutical Research, 22 (12), pp. 2069-2078.

Schuetz, Y. B., Naik, A., Guy, R. H. and Kalia, Y. N., 2005. Emerging strategies for the transdermal delivery of peptide and protein drugs. Expert Opinion on Drug Delivery, 2 (3), pp. 533-548.

Diaz del Consuelo, I., Pizzolato, G. P., Falson, F., Guy, R. H. and Jacques, Y., 2005. Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue. Journal of Pharmaceutical Sciences, 94 (12), pp. 2677-2688.

Sieg, A., Guy, R. H. and Delgado-Charro, M. B., 2005. Noninvasive and minimally invasive methods for transdermal glucose monitoring. Diabetes Technology & Therapeutics, 7 (7), pp. 174-197.

Touraille, G. D., McCarley, K. D., Bunge, A. L., Marty, J. P. and Guy, R. H., 2005. Percutaneous absorption of 4-cyanophenol from freshly contaminated soil in vitro: effects of soil loading and contaminant concentration. Environmental Science & Technology, 39, pp. 3723-3731.

Mehier-Humbert, S. and Guy, R. H., 2005. Physical methods for gene transfer: improving the kinetics of gene delivery into cells. Advanced Drug Delivery Reviews, 57, pp. 733-753.

Mehier-Humbert, S., Yan, F., Guy, R. H. and Bettinger, T., 2005. Plasma membrane poration induced by ultrasound: implication for drug delivery. Journal of Controlled Release, 104, pp. 213-222.

Wascotte, V., Leboulanger, B., Guy, R. H. and Delgado-Charro, M. B., 2005. Reverse iontophoresis of lithium: electrode formulation using a thermoreversible polymer. European Journal of Pharmaceutics and Biopharmaceutics, 59, pp. 237-240.

Schuetz, Y. B., Naik, A., Guy, R. H., Vuaridel, E. and Kalia, Y. N., 2005. Transdermal iontophoretic delivery of triptorelin (Decapeptyl©) in vitro. Journal of Pharmaceutical Sciences, 94 (10), pp. 2175-2182.

Schuetz, Y. B., Naik, A., Guy, R. H., Vuaridel, E. and Kalia, Y. N., 2005. Transdermal iontophoretic delivery of vapreotide acetate across porcine skin in vitro. Pharmaceutical Research, 22 (8), pp. 1305-1312.

Diaz del Consuelo, I., Falson, F., Guy, R. H. and Jacques, Y., 2005. Transport of fentanyl through pig buccal and esophageal epithelia in vitro . Influence of concentration and vehicle pH. Pharmaceutical Research, 22 (9), pp. 1525-1529.

Mehier-Humbert, S., Bettinger, T., Yan, F. and Guy, R. H., 2005. Ultrasound-mediated gene delivery: kinetics of plasmid internalization and gene expression. Journal of Controlled Release, 104, pp. 203-211.

Hadgraft, J. and Guy, R. H., 2004. Biotechnological aspects of transport across human skin. Biotechnology & Genetic Engineering Reviews, 21, pp. 183-193.

Sekkat, N., Kalia, Y. N. and Guy, R. H., 2004. Development of an in vitro model for premature neonatal skin: biophysical characterization using transepidermal water loss. Journal of Pharmaceutical Sciences, 93 (12), pp. 2936-2940.

Sieg, A., Guy, R. H. and Delgado-Charro, M. B., 2004. Electroosmosis in transdermal iontophoresis: implications for noninvasive and calibration-free glucose monitoring. Biophysical Journal, 87, pp. 3344-3350.

Alvarez-Román, R., Naik, A., Kalia, Y. N., Guy, R. H. and Fessi, H., 2004. Enhancement of topical delivery from biodegradable nanoparticles. Pharmaceutical Research, 21 (10), pp. 1818-1825.

Kalia, Y. N., Naik, A., Garrison, J. and Guy, R. H., 2004. Iontophoretic drug delivery. Advanced Drug Delivery Reviews, 56, pp. 619-658.

Leboulanger, B., Aubry, J. M., Bondolfi, G., Guy, R. H. and Delgado-Charro, M. B., 2004. Lithium monitoring by reverse iontophoresis in vivo. Clinical Chemistry, 50 (11), pp. 2091-2100.

Wascotte, V., Delgado-Charro, M. B., Guy, R. H. and Preat, V., 2004. Monitoring renal function by reverse iontophoresis. European Journal of Pharmaceutical Sciences, 23, S57-S57.

Curdy, C., Naik, A., Kalia, Y. N., Alberti, I. and Guy, R. H., 2004. Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo. International Journal of Pharmaceutics, 271, pp. 251-256.

Leboulanger, B., Guy, R. H. and Delgado-Charro, M. B., 2004. Non-invasive monitoring of phenytoin by reverse iontophoresis. European Journal of Pharmaceutical Sciences, 22, pp. 427-433.

Sieg, A., Guy, R. H. and Delgado-Charro, M. B., 2004. Noninvasive glucose monitoring by reverse iontophoresis in vivo: application of the internal standard concept. Clinical Chemistry, 50 (8), pp. 1383-1390.

Lopez, R. F. V., Lange, N., Guy, R. H. and Bentley, M. V. L. B., 2004. Photodynamic therapy of skin cancer: controlled drug delivery of 5-ALA and its esters. Advanced Drug Delivery Reviews, 56, pp. 77-94.

Sekkat, N., Kalia, Y. N. and Guy, R. H., 2004. Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates. Pharmaceutical Research, 21 (8), pp. 1390-1397.

Geinoz, S., Guy, R. H., Testa, B. and Carrupt, P. A., 2004. Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation. Pharmaceutical Research, 21 (1), pp. 83-92.

Leboulanger, B., Fathi, M., Guy, R. H. and Delgado-Charro, M. B., 2004. Reverse iontophoresis as a noninvasive tool for lithium monitoring and pharmacokinetic profiling. Pharmaceutical Research, 21 (7), pp. 1214-1222.

Leboulanger, B., Guy, R. H. and Delgado-Charro, M. B., 2004. Reverse iontophoresis for non-invasive transdermal monitoring. Physiological Measurement, 25, R35-R50.

Sieg, A., Guy, R. H. and Delgado-Charro, M. B., 2004. Simultaneous extraction of urea and glucose by reverse iontophoresis in vivo. Pharmaceutical Research, 21 (10), pp. 1805-1810.

Alvarez-Román, R., Naik, A., Kalia, Y. N., Guy, R. H. and Fessi, H., 2004. Skin penetration and distribution of polymeric nanoparticles. Journal of Controlled Release, 99, pp. 53-62.

Merclin, N., Bender, J., Sparr, E., Guy, R. H., Ehrsson, H. and Engström, S., 2004. Transdermal delivery from a lipid sponge phase - iontophoretic and passive transport in vitro of 5-aminolevulinic acid and its methyl ester. Journal of Controlled Release, 100 (2), pp. 191-198.

Alvarez-Román, R., Naik, A., Kalia, Y. N., Fessi, H. and Guy, R. H., 2004. Visualization of skin penetration using confocal laser scanning microscopy. European Journal of Pharmaceutics and Biopharmaceutics, 58, pp. 301-316.

Lopez, R. F. V., Bentley, M. V. L. B., Delgado-Charro, M. B., Salomon, D., van den Bergh, H., Lange, N. and Guy, R. H., 2003. Enhanced delivery of 5-aminolevulinic acid esters by iontophoresis in vitro. Photochemistry and Photobiology, 77 (3), pp. 304-308.

Merino, G., Kalia, Y. N., Delgado-Charro, M. B., Potts, R. O. and Guy, R. H., 2003. Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis. Journal of Controlled Release, 88, pp. 85-94.

Lopez, R. F. V., Bentley, M. V. L. B., Delgado-Charro, M. B. and Guy, R. H., 2003. Optimization of aminolevulinic acid delivery by iontophoresis. Journal of Controlled Release, 88, pp. 65-70.

Sieg, A., Guy, R. H. and Delgado-Charro, M. B., 2003. Reverse iontophoresis for non-invasive glucose monitoring: the internal standard concept. Journal of Pharmaceutical Sciences, 92 (11), pp. 2295-2302.

Leboulanger, B., Guy, R. H. and Delgado-Charro, M. B., 2003. Reverse iontophoretic monitoring of free phenytoin. Therapeutic Drug Monitoring, 25 (4), p. 499.

Leboulanger, B., Aubry, J. M., Bondolfi, G., Guy, R. H. and Delgado-Charro, M. B., 2003. Reverse iontophoretic monitoring of lithium in vivo. Therapeutic Drug Monitoring, 25 (4), p. 499.

Alvarez-Román, R., Merino, G., Kalia, Y. N., Naik, A. and Guy, R. H., 2003. Skin permeability enhancement by low frequency sonophoresis: lipid extraction and transport pathways. Journal of Pharmaceutical Sciences, 92 (6), pp. 1138-1146.

Delgado-Charro, M. B. and Guy, R. H., 2003. Transdermal reverse iontophoresis of valproate: a non-invasive method for therapeutic drug monitoring. Pharmaceutical Research, 20 (9), pp. 1508-1513.

Merino, G., Kalia, Y. N. and Guy, R. H., 2003. Ultrasound-enhanced transdermal transport. Journal of Pharmaceutical Sciences, 92 (6), pp. 1125-1137.

Sekkat, N., Kalia, Y. N. and Guy, R. H., 2002. Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo. Journal of Pharmaceutical Sciences, 91 (11), pp. 2376-2381.

Reddy, M. B., Stinchcomb, A. L., Guy, R. H. and Bunge, A. L., 2002. Determining dermal absorption parameters in vivo from tape strip data. Pharmaceutical Research, 19 (3), pp. 292-298.

Dujardin, N., Staes, E., Kalia, Y. N., Clarys, P., Guy, R. H. and Préat, V., 2002. In vivo assessment of skin electroporation using square wave pulses. Journal of Controlled Release, 79, pp. 219-227.

Veuillez, F., Falson-Rieg, F., Guy, R. H., Deshusses, J. and Buri, P., 2002. Permeation of a myristoylated dipeptide across the buccal mucosa: topological distribution and evaluation of tissue integrity. International Journal of Pharmaceutics, 231 (1), pp. 1-9.

Curdy, C., Kalia, Y. N. and Guy, R. H., 2002. Post-iontophoresis recovery of human skin impedance in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 53, pp. 15-21.

Geinoz, S., Rey, S., Boss, G., Bunge, A. L., Guy, R. H., Carrupt, P. A., Reist, M. and Testa, B., 2002. Quantitative structure-permeation relationships for solute transport across silicone membranes. Pharmaceutical Research, 19 (11), pp. 1622-1629.

Sekkat, N., Naik, A., Kalia, Y. N., Glikfeld, P. and Guy, R. H., 2002. Reverse iontophoretic monitoring in premature neonates: feasibility and potential. Journal of Controlled Release, 81, pp. 83-89.

Alberti, I., Kalia, Y. N., Naik, A. and Guy, R. H., 2001. Assessment and prediction of the cutaneous bioavailability of topical terbinafine, in vivo , in man. Pharmaceutical Research, 18 (10), pp. 1472-1475.

Kalia, Y. N., Alberti, I., Naik, A. and Guy, R. H., 2001. Assessment of topical bioavailability in vivo: the importance of stratum corneum thickness. Skin Pharmacology and Applied Skin Physiology, 14 (Suppl 1), pp. 82-86.

Alvarez-Román, R., Barré, G., Guy, R. H. and Fessi, H., 2001. Biodegradable polymer nanocapsules containing a sunscreen agent: preparation and photoprotection. European Journal of Pharmaceutics and Biopharmaceutics, 52, pp. 191-195.

Marro, D., Guy, R. H. and Delgado-Charro, M. B., 2001. Characterization of the iontophoretic permselectivity properties of human and pig skin. Journal of Controlled Release, 70 (1-2), pp. 213-217.

Marro, D., Kalia, Y. N., Delgado-Charro, M. B. and Guy, R. H., 2001. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Pharmaceutical Research, 18 (12), pp. 1701-1708.

Alberti, I., Kalia, Y. N., Naik, A., Bonny, J. D. and Guy, R. H., 2001. Effect of ethanol and isopropyl myristate on the bioavailability of topical terbinafine in human stratum corneum, in vivo. International Journal of Pharmaceutics, 219, pp. 11-19.

Moser, K., Kriwet, K., Kalia, Y. N. and Guy, R. H., 2001. Enhanced skin permeation of a lipophilic drug using supersaturated formulations. Journal of Controlled Release, 73, pp. 245-253.

Alberti, I., Kalia, Y. N., Naik, A., Bonny, J. D. and Guy, R. H., 2001. In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum. Journal of Controlled Release, 71, pp. 319-327.

Lopez, R. F. V., Bentley, M. V. L. B., Delgado-Charro, M. B. and Guy, R. H., 2001. Iontophoretic delivery of 5-aminolevulinic acid (ALA): effect of pH. Pharmaceutical Research, 18 (3), pp. 311-315.

Guy, R. H., Delgado-Charro, M. B. and Kalia, Y. N., 2001. Iontophoretic transport across the skin. Skin Pharmacology and Applied Skin Physiology, 14 (Suppl 1), pp. 35-40.

Kalia, Y. N. and Guy, R. H., 2001. Modeling transdermal drug release. Advanced Drug Delivery Reviews, 48, pp. 159-172.

Curdy, C., Kalia, Y. N. and Guy, R. H., 2001. Non-invasive assessment of the effects of iontophoresis on human skin in-vivo. Journal of Pharmacy and Pharmacology, 53, pp. 769-777.

Marro, D., Kalia, Y. N., Delgado-Charro, M. B. and Guy, R. H., 2001. Optimizing iontophoretic drug delivery: identification and distribution of the charge-carrying species. Pharmaceutical Research, 18 (12), pp. 1709-1713.

Moser, K., Kriwet, K., Naik, A., Kalia, Y. N. and Guy, R. H., 2001. Passive skin penetration enhancement and its quantification in vitro. European Journal of Pharmaceutics and Biopharmaceutics, 52, pp. 103-112.

Moser, K., Kriwet, K., Froehlich, C., Naik, A., Kalia, Y. N. and Guy, R. H., 2001. Permeation enhancement of a highly lipophilic drug using supersaturated systems. Journal of Pharmaceutical Sciences, 90 (5), pp. 607-616.

Curdy, C., Kalia, Y. N., Naik, A. and Guy, R. H., 2001. Piroxicam delivery into human stratum corneum in vivo: iontophoresis versus passive diffusion. Journal of Controlled Release, 76, pp. 73-79.

Moser, K., Kriwet, K., Kalia, Y. N. and Guy, R. H., 2001. Stabilization of supersaturated solutions of a lipophilic drug for dermal delivery. International Journal of Pharmaceutics, 224, pp. 169-176.

Moser, K., Kriwet, K., Froehlich, C., Kalia, Y. N. and Guy, R. H., 2001. Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug. Pharmaceutical Research, 18 (7), pp. 1006-1011.

Delgado-Charro, M. B. and Guy, R. H., 2001. Transdermal iontophoresis for controlled drug delivery and non-invasive monitoring. STP Pharma Sciences, 11 (6), pp. 404-414.

This list was generated on Sat Dec 20 13:58:39 2014 GMT.