Research

Items by Holman, Geoffrey

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Number of items: 45.

2014

Betts, J., Richardson, J. D., Chowdhury, E., Holman, G. D., Tsintzas, K. and Thompson, D., 2014. The causal role of breakfast in energy balance and health : A randomized controlled trial in lean adults. The American Journal of Clinical Nutrition, 100 (2), pp. 539-547.

Betts, J., Richardson, J. D., Chowdhury, E., Holman, G. D., Tsintzas, K. and Thompson, D., 2014. Forthcoming. The causal role of breakfast in energy balance and health: a randomized controlled trial in lean adults. : ISRCTN31521726. [Dataset]

2013

Feng, Y., Williams, B. G., Koumanov, F., Wolstenholme, A. J. and Holman, G. D., 2013. FGT-1 is The major glucose transporter in C. elegans and is central to aging pathways. Biochemical Journal, 456 (2), pp. 219-229.

2012

Koumanov, F., Pereira, V. J., Whitley, P. R. and Holman, G. D., 2012. GLUT4 Traffic through an ESCRT-III-Dependent Sorting Compartment in Adipocytes. PLoS ONE, 7 (9), e44141.

Holman, G., 2012. Reagent. C07H19/20 -WO2012049464 (A1), 19 April 2012.

2011

Betts, J. A., Thompson, D., Richardson, J. D., Chowdhury, E. A., Jeans, M., Holman, G. D. and Tsintzas, K., 2011. Bath Breakfast Project (BBP) - Examining the Role of Extended Daily Fasting in Human Energy Balance and Associated Health Outcomes: study protocol for a randomised controlled trial [ISRCTN31521726]. Trials, 12, 172.

Koumanov, F., Richardson, J. D., Murrow, B. A. and Holman, G. D., 2011. AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane. Journal of Biological Chemistry, 286 (19), pp. 16574-16582.

2010

Lawrence, S. P., Holman, G. D. and Koumanov, F., 2010. Translocation of the Na+/H+ exchanger 1 (NHE1) in cardiomyocyte responses to insulin and energy-status signalling. Biochemical Journal, 432 (3), pp. 515-523.

Fazakerley, D. J., Holman, G. D., Marley, A., James, D. E., Stockli, J. and Coster, A. C. F., 2010. Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes. Journal of Biological Chemistry, 285 (3), pp. 1653-1660.

Stöckli, J., Fazakerley, D. J., Coster, A. C. F., Holman, G. D. and James, D. E., 2010. Muscling in on GLUT4 kinetics. Communicative & Integrative Biology, 3 (3), pp. 260-262.

2009

Karlsson, H. K. R., Chibalin, A. V., Koistinen, H. A., Yang, J., Koumanov, F., Wallberg-Henriksson, H., Zierath, J. R. and Holman, G. D., 2009. Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes, 58 (4), pp. 847-854.

Fazakerley, D. J., Lawrence, S. P., Lizunov, V. A., Cushman, S. W. and Holman, G. D., 2009. A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling. Journal of Cell Science, 122 (5), pp. 727-734.

2008

Sakamoto, K. and Holman, G. D., 2008. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. American Journal of Physiology: Endocrinology and Metabolism, 295 (1), E29-E37.

Holman, G. D. and Sakamoto, K., 2008. Regulating the motor for GLUT4 vesicle traffic. Cell Metabolism, 8 (5), pp. 344-346.

2007

Miller, E. J., Li, J., Sinusas, K. M., Holman, G. D. and Young, L. H., 2007. Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American Journal of Physiology: Endocrinology and Metabolism, 292 (6), E1922-E1928.

Koumanov, F. and Holman, G. D., 2007. Thrifty Tbc1d1 and Tbc1d4 proteins link signalling and membrane trafficking pathways. Biochemical Journal, 403, e9-11.

2006

Gillings, A. S., Yang, J., Marley, A. E., Holman, G. D., Peckham, M., Kilgour, E. and Baldwin, S. A., 2006. Investigation of the role of Kv1.3 as a potential regulator of peripheral insulin sensitivity. Diabetologia, 49, p. 366.

Yang, J. and Holman, G. D., 2006. Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis. Endocrinology, 147 (6), pp. 2728-2736.

2005

Ribe, D., Yang, J., Patel, S., Koumanov, F. O., Cushman, S. W. and Holman, G. D., 2005. Endofacial competitive inhibition of glucose transporter-4 intrinsic activity by the mitogen-activated protein kinase inhibitor SB203580. Endocrinology, 146 (4), pp. 1713-1717.

Yang, J. and Holman, G. D., 2005. Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes. Journal of Biological Chemistry, 280 (6), pp. 4070-4078.

Koumanov, F., Jin, B., Yang, J. and Holman, G. D., 2005. Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step. Cell Metabolism, 2 (3), pp. 179-189.

Collison, M., James, D. J., Graham, D., Holman, G. D., Connell, J. M. C., Dominiczak, A. F., Gould, G. W. and Salt, I. P., 2005. Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3), pp. 539-546.

Coward, R. J. M., Welsh, G. I., Yang, J., Tasman, C., Lennon, R., Koziell, A., Satchell, S., Holman, G. D., Kerjaschki, D., Tavare, J. M., Mathieson, P. W. and Saleem, M. A., 2005. The human glomerular podocyte is a novel target for insulin action. Diabetes, 54 (11), pp. 3095-3102.

2004

Li, J., Hu, X. Y., Selvakumar, P., Russell, R. R., Cushman, S. W., Holman, G. D. and Young, L. H., 2004. Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. American Journal of Physiology: Endocrinology and Metabolism, 287 (5), E834-E841.

Tatibouet, A., Lawrence, S., Rollin, P. and Holman, G. D., 2004. Selective formation of 1,3-oxazolidine-2-thiones on ketohexose templates. Synlett

2003

Koistinen, H. A., Galuska, D., Chibalin, A. V., Yang, J., Zierath, J. R., Holman, G. D. and Wallberg-Henriksson, H., 2003. 5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes, 52 (5), pp. 1066-1072.

Coward, R. J. M., Welsh, G. I., Holman, G. D., Kerjaschki, D., Tavare, J. M., Mathieson, P. W. and Saleem, M. A., 2003. Human podocytes rapidly utilize glucose by both GLUT1 and GLUT4 in response to insulin; with significant differences in glucose transporter levels occurring in diabetic nephropathy. Journal of the American Society of Nephrology, 14, 388A-388A.

Girniene, J., Tatibouet, A., Sackus, A., Yang, J., Holman, G. D. and Rollin, P., 2003. Inhibition of the D-fructose transporter protein GLUT5 by fused-ring glyco-1,3-oxazolidin-2-thiones and -oxazolidin-2-ones. Carbohydrate Research, 338 (8), pp. 711-719.

Al-Khalili, L., Chibalin, A. V., Kannisto, K., Zhang, B. B., Permert, J., Holman, G. D., Ehrenborg, E., Ding, V. D. H., Zierath, J. R. and Krook, A., 2003. Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content. Cellular and Molecular Life Sciences (CMLS), 60 (5), pp. 991-998.

Bentley, J., Itchayanan, D., Barnes, K., McIntosh, E., Tang, X. W., Downes, C. P., Holman, G. D., Whetton, A. D., Owen-Lynch, P. J. and Baldwin, S. A., 2003. Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface. Journal of Biological Chemistry, 278 (41), pp. 39337-39348.

2002

Whitley, P., Gibbard, A. M., Koumanov, F., Oldfield, S., Kilgour, E. E., Prestwich, G. D. and Holman, G. D., 2002. Identification of centaurin-alpha 2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle. European Journal of Cell Biology, 81 (4), pp. 222-230.

Yang, J., Dowden, J., Tatibouet, A., Hatanaka, Y. and Holman, G. D., 2002. Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5. Biochemical Journal, 367, pp. 533-539.

Hashimoto, M., Yang, J., Hatanaka, Y., Sadakane, Y., Nakagomi, K. and Holman, G. D., 2002. Improvement in the properties of 3-phenyl-3-trifluoromethyldiazirine based photoreactive bis-glucose probes for GLUT4 following substitution on the phenyl ring. Chemical & Pharmaceutical Bulletin, 50 (7), pp. 1004-1006.

Yang, J., Hodel, A. and Holman, G. D., 2002. Insulin and isoproterenol have opposing roles in the maintenance of cytosol pH and optimal fusion of GLUT4 vesicles with the plasma membrane. Journal of Biological Chemistry, 277 (8), pp. 6559-6566.

2001

Hashimoto, M., Yang, J. and Holman, G. D., 2001. Cell-surface recognition of biotinylated membrane proteins requires very long spacer arms: An example from glucose-transporter probes. ChemBiochem, 2 (1), pp. 52-59.

Buhl, E. S., Jessen, N., Schmitz, O., Pedersen, S. B., Pedersen, O., Holman, G. D. and Lund, S., 2001. Chronic treatment with 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner. Diabetes, 50 (1), pp. 12-17.

Tatibouet, A., Lefoix, M., Nadolny, J., Martin, O. R., Rollin, P., Yang, J. and Holman, G. D., 2001. D-Fructose-L-sorbose interconversions. Access to 5-thio-D-fructose and interaction with the D-fructose transporter, GLUT5. Carbohydrate Research, 333 (4), pp. 327-334.

Holman, G. D. and Sandoval, I. V., 2001. Moving the insulin-regulated glucose transporter GLUT4 into and out of storage. Trends in Cell Biology, 11 (4), pp. 173-179.

Hashimoto, M., Hatanaka, Y., Yang, J., Dhesi, J. and Holman, G. D., 2001. Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling. Carbohydrate Research, 331 (2), pp. 119-127.

2000

Pryor, P. R., Liu, S. C. H., Clark, A. E., Yang, J., Holman, G. D. and Tosh, D., 2000. Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin. Biochemical Journal, 348 (1), pp. 83-91.

Sandoval, I. V., Martinez-Arca, S., Valdueza, J., Palacios, S. and Holman, G. D., 2000. Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4. Journal of Biological Chemistry, 275 (51), pp. 39874-39885.

Tatibouet, A., Yang, J., Morin, C. and Holman, G. D., 2000. Synthesis and evaluation of fructose analogues as inhibitors of the D-fructose transporter GLUT5. Bioorganic and Medicinal Chemistry, 8 (7), pp. 1825-1833.

Ryder, J. W., Yang, J., Galuska, D., Rincon, J., Bjornholm, M., Krook, A., Lund, S., Pedersen, O., Wallberg-Henriksson, H., Zierath, J. R. and Holman, G. D., 2000. Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients. Diabetes, 49 (4), pp. 647-654.

1999

Gillingham, A. K., Koumanov, F., Pryor, P. R., Reaves, B. J. and Holman, G. D., 1999. Association of AP1 adaptor complexes with GLUT4 vesicles. Journal of Cell Science, 112 (24), pp. 4793-4800.

1996

Malide, D., Tosh, D., Clark, A. E., Cushman, S. W. and Holman, G. D., 1996. Altered GLUT4 subcellular trafficking in primary adipose cell cultures: Immunocytochemical evidence. Molecular Biology of the Cell, 7, p. 2636.

This list was generated on Fri Nov 28 23:49:24 2014 GMT.