Items by Holman, Geoffrey

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Number of items: 55.

Nathubhai, A., Haikarainen, T., Koivunen, J., Murthy, S., Koumanov, F., Lloyd, M., Holman, G., Pihlajaniemi, T., Tosh, D., Lehtio, L. and Threadgill, M., 2017. Highly potent and isoform-selective dual-site-binding tankyrase/Wnt signaling inhibitors that increase cellular glucose uptake and have anti-proliferative activity. Journal of Medicinal Chemistry, 60 (2), pp. 814-820. Item availability may be restricted.

Zhou, Z., Menzel, F., Benninghoff, T., Chadt, A., Du, C., Holman, G. D. and Al-Hasani, H., 2017. Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking. FEBS Letters, 591 (1), pp. 88-96.

Fazakerley, D. J., Naghiloo, S., Chaudhuri, R., Koumanov, F., Burchfield, J. G., Thomas, K. C., Krycer, J. R., Prior, M. J., Parker, B. L., Murrow, B. A., Stöckli, J., Meoli, C. C., Holman, G. D. and James, D. E., 2015. Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumour Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes. The Journal of biological chemistry, 290, pp. 23528-23542.

Chadt, A., Immisch, A., De Wendt, C., Springer, C., Zhou, Z., Stermann, T., Holman, G. D., Loffing-cueni, D., Loffing, J., Joost, H.-g. and Al-hasani, H., 2015. Deletion of Both Rab-GTPase–Activating Proteins TBC1D1 and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport. Diabetes, 64 (3), pp. 746-759.

Feng, Y., Williams, B. G., Koumanov, F., Wolstenholme, A. J. and Holman, G. D., 2013. FGT-1 is The major glucose transporter in C. elegans and is central to aging pathways. Biochemical Journal, 456 (2), pp. 219-229.

Holman, G., 2012. Reagent. C07H19/20 - WO2012049464 (A1), 19 April 2012.

Fazakerley, D. J., Holman, G. D., Marley, A., James, D. E., Stockli, J. and Coster, A. C. F., 2010. Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes. Journal of Biological Chemistry, 285 (3), pp. 1653-1660.

Stöckli, J., Fazakerley, D. J., Coster, A. C. F., Holman, G. D. and James, D. E., 2010. Muscling in on GLUT4 kinetics. Communicative & Integrative Biology, 3 (3), pp. 260-262.

Karlsson, H. K. R., Chibalin, A. V., Koistinen, H. A., Yang, J., Koumanov, F., Wallberg-Henriksson, H., Zierath, J. R. and Holman, G. D., 2009. Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes, 58 (4), pp. 847-854.

Fazakerley, D. J., Lawrence, S. P., Lizunov, V. A., Cushman, S. W. and Holman, G. D., 2009. A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling. Journal of Cell Science, 122 (5), pp. 727-734.

Sakamoto, K. and Holman, G. D., 2008. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. American Journal of Physiology: Endocrinology and Metabolism, 295 (1), E29-E37.

Holman, G. D. and Sakamoto, K., 2008. Regulating the motor for GLUT4 vesicle traffic. Cell Metabolism, 8 (5), pp. 344-346.

Miller, E. J., Li, J., Sinusas, K. M., Holman, G. D. and Young, L. H., 2007. Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American Journal of Physiology: Endocrinology and Metabolism, 292 (6), E1922-E1928.

Gillings, A. S., Yang, J., Marley, A. E., Holman, G. D., Peckham, M., Kilgour, E. and Baldwin, S. A., 2006. Investigation of the role of Kv1.3 as a potential regulator of peripheral insulin sensitivity. Diabetologia, 49, p. 366.

Collison, M., James, D. J., Graham, D., Holman, G. D., Connell, J. M. C., Dominiczak, A. F., Gould, G. W. and Salt, I. P., 2005. Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats. Diabetologia, 48 (3), pp. 539-546.

Coward, R. J. M., Welsh, G. I., Yang, J., Tasman, C., Lennon, R., Koziell, A., Satchell, S., Holman, G. D., Kerjaschki, D., Tavare, J. M., Mathieson, P. W. and Saleem, M. A., 2005. The human glomerular podocyte is a novel target for insulin action. Diabetes, 54 (11), pp. 3095-3102.

Li, J., Hu, X. Y., Selvakumar, P., Russell, R. R., Cushman, S. W., Holman, G. D. and Young, L. H., 2004. Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. American Journal of Physiology: Endocrinology and Metabolism, 287 (5), E834-E841.

Tatibouet, A., Lawrence, S., Rollin, P. and Holman, G. D., 2004. Selective formation of 1,3-oxazolidine-2-thiones on ketohexose templates. Synlett

Koistinen, H. A., Galuska, D., Chibalin, A. V., Yang, J., Zierath, J. R., Holman, G. D. and Wallberg-Henriksson, H., 2003. 5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes, 52 (5), pp. 1066-1072.

Coward, R. J. M., Welsh, G. I., Holman, G. D., Kerjaschki, D., Tavare, J. M., Mathieson, P. W. and Saleem, M. A., 2003. Human podocytes rapidly utilize glucose by both GLUT1 and GLUT4 in response to insulin; with significant differences in glucose transporter levels occurring in diabetic nephropathy. Journal of the American Society of Nephrology, 14, 388A-388A.

Whitley, P., Reaves, B. J., Hashimoto, M., Riley, A. M., Potter, B. V. L. and Holman, G. D., 2003. Identification of mammalian Vps24p as an effector of phosphatidylinosital 3,5-bisphosphate-dependent endosome compartmentalization. Journal of Biological Chemistry, 278 (40), pp. 38786-38795.

Girniene, J., Tatibouet, A., Sackus, A., Yang, J., Holman, G. D. and Rollin, P., 2003. Inhibition of the D-fructose transporter protein GLUT5 by fused-ring glyco-1,3-oxazolidin-2-thiones and -oxazolidin-2-ones. Carbohydrate Research, 338 (8), pp. 711-719.

Al-Khalili, L., Chibalin, A. V., Kannisto, K., Zhang, B. B., Permert, J., Holman, G. D., Ehrenborg, E., Ding, V. D. H., Zierath, J. R. and Krook, A., 2003. Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content. Cellular and Molecular Life Sciences (CMLS), 60 (5), pp. 991-998.

Bentley, J., Itchayanan, D., Barnes, K., McIntosh, E., Tang, X. W., Downes, C. P., Holman, G. D., Whetton, A. D., Owen-Lynch, P. J. and Baldwin, S. A., 2003. Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface. Journal of Biological Chemistry, 278 (41), pp. 39337-39348.

Yang, J., Gillingham, A. K., Hodel, A., Koumanov, F., Woodward, B. and Holman, G., 2002. Insulin-stimulated cytosol alkalinization facilitates optimal activation of glucose transport in cardiomyocytes. American Journal of Physiology: Endocrinology and Metabolism, 283 (6), E1299-E1307.

Whitley, P., Gibbard, A. M., Koumanov, F., Oldfield, S., Kilgour, E. E., Prestwich, G. D. and Holman, G. D., 2002. Identification of centaurin-alpha 2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle. European Journal of Cell Biology, 81 (4), pp. 222-230.

Yang, J., Dowden, J., Tatibouët, A., Hatanaka, Y. and Holman, G. D., 2002. Development of high-affinity ligands and photoaffinity labels for the D-fructose transporter GLUT5. Biochemical Journal, 367 (2), pp. 533-539.

Hashimoto, M., Yang, J., Hatanaka, Y., Sadakane, Y., Nakagomi, K. and Holman, G. D., 2002. Improvement in the properties of 3-phenyl-3-trifluoromethyldiazirine based photoreactive bis-glucose probes for GLUT4 following substitution on the phenyl ring. Chemical & Pharmaceutical Bulletin, 50 (7), pp. 1004-1006.

Tatibouet, A., Lefoix, M., Nadolny, J., Martin, O. R., Rollin, P., Yang, J. and Holman, G. D., 2001. D-Fructose-L-sorbose interconversions. Access to 5-thio-D-fructose and interaction with the D-fructose transporter, GLUT5. Carbohydrate Research, 333 (4), pp. 327-334.

Holman, G. D. and Sandoval, I. V., 2001. Moving the insulin-regulated glucose transporter GLUT4 into and out of storage. Trends in Cell Biology, 11 (4), pp. 173-179.

Hashimoto, M., Hatanaka, Y., Yang, J., Dhesi, J. and Holman, G. D., 2001. Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling. Carbohydrate Research, 331 (2), pp. 119-127.

Pryor, P. R., Liu, S. C. H., Clark, A. E., Yang, J., Holman, G. D. and Tosh, D., 2000. Chronic insulin effects on insulin signalling and GLUT4 endocytosis are reversed by metformin. Biochemical Journal, 348 (1), pp. 83-91.

Tatibouet, A., Yang, J., Morin, C. and Holman, G. D., 2000. Synthesis and evaluation of fructose analogues as inhibitors of the D-fructose transporter GLUT5. Bioorganic and Medicinal Chemistry, 8 (7), pp. 1825-1833.

Ryder, J. W., Yang, J., Galuska, D., Rincon, J., Bjornholm, M., Krook, A., Lund, S., Pedersen, O., Wallberg-Henriksson, H., Zierath, J. R. and Holman, G. D., 2000. Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients. Diabetes, 49 (4), pp. 647-654.

Gillingham, A. K., Koumanov, F., Pryor, P. R., Reaves, B. J. and Holman, G. D., 1999. Association of AP1 adaptor complexes with GLUT4 vesicles. Journal of Cell Science, 112 (24), pp. 4793-4800.

Malide, D., Tosh, D., Clark, A. E., Cushman, S. W. and Holman, G. D., 1996. Altered GLUT4 subcellular trafficking in primary adipose cell cultures: Immunocytochemical evidence. Molecular Biology of the Cell, 7, p. 2636.

This list was generated on Sat May 27 11:10:07 2017 IST.