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Items by Mills, Stephen

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Number of items: 25.

Grint, T., Riley, A. M., Mills, S. J., Potter, B. V. L. and Safrany, S. T., 2012. Fibrinogen—a possible extracellular target for inositol phosphates. Messenger, 1 (2), pp. 160-166.

Mills, S. J., Persson, C., Cozier, G., Thomas, M. P., Trésaugues, L., Erneux, C., Riley, A. M., Nordlund, P. and Potter, B. V. L., 2012. A synthetic polyphosphoinositide headgroup surrogate in complex with SHIP2 provides a rationale for drug discovery. ACS Chemical Biology, 7 (5), pp. 822-828.

Mills, S. J., Vandeput, F., Trusselle, M. N., Safrany, S. T., Erneux, C. and Potter, B. V. L., 2008. Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5‐trisphosphate 5‐phosphatase and interaction with the PH domain of protein kinase Bα. ChemBiochem, 9 (11), pp. 1757-1766.

Vandeput, F., Combettes, L., Mills, S. J., Backers, K., Wohlkönig, A., Parys, J. B., De Smedt, H., Missiaen, L., Dupont, G., Potter, B. V. L. and Erneux, C., 2007. Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca 2+ responses in rat hepatocytes. FASEB Journal, 21 (7), pp. 1481-1491.

Mills, S. J., Komander, D., Trusselle, M. N., Safrany, S. T., van Aalten, D. M. F. and Potter, B. V. L., 2007. Novel inositol phospholipid headgroup surrogate crystallized in the pleckstrin homology domain of protein kinase Bα. ACS Chemical Biology, 2 (4), pp. 242-246.

Mills, S. J., Dozol, H., Vandeput, F., Backers, K., Woodman, T., Erneux, C., Spiess, B. and Potter, B. V. L., 2006. 3-hydroxybenzene 1,2,4-trisphosphate, a novel second messenger mimic and unusual substrate for type-I myo-inositol 1,4,5-trisphosphate 5-phosphatase : synthesis and physicochemistry. ChemBiochem, 7 (11), pp. 1696-1706.

Poinas, A., Backers, K., Riley, A. M., Mills, S. J., Moreau, C., Potter, B. V. L. and Erneux, C., 2005. Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analogues. ChemBiochem, 6, pp. 1449-1457.

Poinas, A., Backers, K., Riley, A. M., Mills, S. J., Moreau, C., Potter, B. V. L. and Erneux, C., 2005. Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analogues. ChemBiochem, 6 (8), pp. 1449-1457.

Kunerth, S., Langhorst, M. F., Schwarzmann, N., Gu, X., Huang, L., Yang, Z., Zhang, L., Mills, S. J., Zhang, L.-h., Potter, B. V. L. and Guse, A. H., 2004. Amplification and propagation of pacemaker Ca 2+ signals by cyclic ADP-ribose and the type 3 ryanodine receptor in T cells. Journal of Cell Science, 117, pp. 2141-2149.

Horne, G., Mills, S. J. and Potter, B. V. L., 2004. First derivatives of myo-inositol 1,4,6-trisphosphate modified at positions 2 and 3 : structural an analogues of D- myo -inositol 1,4,5-trisphosphate. Carbohydrate Research, 339, pp. 51-65.

Mills, S. J., Riley, A. M., Liu, C., Mahon, M. F. and Potter, B. V. L., 2003. A definitive synthesis of D-myo-inositol 1,4,5,6-tetrakisphosphate and its enantiomer D-myo-inositol 3,4,5,6-tetrakisphosphate from a novel butane-2,3-diacetal-protected inositol. Chemistry - A European Journal, 9 (24), pp. 6207-6214.

Mills, S. J., Backers, K., Erneux, C. and Potter, B. V. L., 2003. Synthesis of D- and L-myo-inisitol 1,2,4,6-tetrakisphosphate regioisomers of myo -inisitol 1,3,4,5 tetrakisphosphate : activity against Ins(1,4,5)P3 binding proteins. Organic & Biomolecular Chemistry, 2003 (1), pp. 3546-3556.

Mills, S. J. and Potter, B. V. L., 2003. Synthesis of potent Ins(1,4,5)P3 5-phosphatase inhibitors by modification of myo -inositol 1,3,4,6-tetrakisphosphate. Bioorganic and Medicinal Chemistry, 11 (19), pp. 4245-4253.

Mills, S. J., Liu, C. and Potter, B. V. L., 2002. Synthesis of D-and L-myo -inositol 2,4,5-trisphosphate and trisphosphorothioate : structural analogues of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research, 337 (20), pp. 1795-1801.

Ukhanov, K., Mills, S. J., Potter, B. V. L. and Walz, B., 2001. InsP3 -induced Ca2+ release in permeabilized invertebrate photoreceptors : a link between phototransduction and Ca2+ stores. Cell Calcium, 29 (5), pp. 335-345.

Hirst, P. H., Riley, A. M., Mills, S. J., Spiers, I. D., Poyner, D. R., Freeman, S., Potter, B. V. L. and Smith, A. W., 1999. Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa. Journal of Applied Microbiology, 86 (3), pp. 537-543.

Hirata, M., Takeuchi, H., Riley, A. M., Mills, S. J., Watanabe, Y. and Potter, B. V. L., 1997. Inositol 1,4,5-trisphosphate receptor subtypes differentially recognize regioisomers of D-myo-inositol 1,4,5-trisphosphate. Biochemical Journal, 328 (1), pp. 93-98.

Mills, S. J. and Potter, B. V. L., 1996. Synthesis of D- and L- myo-inositol 1,4,6-trisphosphate, regioisomers of a ubiquitous second messenger. Journal of Organic Chemistry, 61 (25), pp. 8980-8987.

Ward, S. G., Mills, S. J., Liu, C., Westwick, J. and Potter, B. V. L., 1995. D-myo-inositol 1,4,5-trisphosphate analogues modified at the 3-position inhibit phosphatidylinositol 3-kinase. Journal of Biological Chemistry, 270 (20), pp. 12075-12084.

Mills, S. J., Riley, A. M., Murphy, C. T., Bullock, A. J., Westwick, J. and Potter, B. V. L., 1995. Myo-inositol 1,4,6-trisphosphorothioate and myo-inositol 1,3,4-trisphosphorothioate: new synthetic Ca2+-mobilising partial agonists at the inositol 1,4,5-trisphosphate receptor. Bioorganic & Medicinal Chemistry Letters, 5 (3), pp. 203-208.

Safrany, S. T., Mills, S. J., Liu, C., Lampe, D., Noble, N. J., Nahorski, S. R. and Potter, B. V. L., 1994. Design of potent and selective inhibitors of myo-Inositol 1,4,5-trisphosphate 5-phosphatase. Biochemistry, 33 (35), pp. 10763-10769.

Wilcox, R. A., Safrany, S. T., Lampe, D., Mills, S. J., Nahorski, S. R. and Potter, B. V. L., 1994. Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities. European Journal of Biochemistry, 223 (1), pp. 115-124.

Mills, S. J., Al-hafidh, J., Westwick, J. and Potter, B. V.L., 1993. Myo-inositol 1,4,6-trisphosphate: A new synthetic Ca2+-mobilising inositol phosphate. Bioorganic & Medicinal Chemistry Letters, 3 (12), pp. 2599-2604.

Mills, S. J., Safrany, S. T., Wilcox, R. A., Nahorski, S. R. and Potter, B. V. L., 1993. Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate. Bioorganic & Medicinal Chemistry Letters, 3 (8), pp. 1505-1510.

Lampe, D., Mills, S. J. and Potter, B. V. L., 1992. Total synthesis of the second messenger analogue D-myo-inositol 1-phosphorothioate 4,5-bisphosphate: optical resolution of DL-1-O-allyl-2,3,6-tri-O-benzyl-myo-inositol and fluorescent labelling of myo-inositol 1,4,5-trisphosphate. Journal of the Chemical Society - Perkin Transcriptions 1, 1992 (21), pp. 2899-2906.

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