Items by Welham, Melanie

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Number of items: 41.


Kia, R., Kelly, L., Sison-Young, R. L. C., Zhang, F., Pridgeon, C. S., Heslop, J. A., Metcalfe, P., Kitteringham, N. R., Baxter, M., Harrison, S., Hanley, N. A., Burke, Z. D., Storm, M. P., Welham, M. J., Tosh, D., Küppers-Munther, B., Edsbagge, J., Starkey Lewis, P. J., Bonner, F., Harpur, E., Sidaway, J., Bowes, J., Fenwick, S. W., Malik, H., Goldring, C. E. P. and Kevin Park, B., 2015. MicroRNA-122:A novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity. Toxicological Sciences, 144 (1), pp. 173-185.



Turinetto, V., Orlando, L., Sanchez Ripoll, Y., Kumpfmueller, B., Storm, M. P., Porcedda, P., Minieri, V., Saviozzi, S., Accomasso, L., Cibrario Rocchietti, E., Moorwood, K., Circosta, P., Cignetti, A., Welham, M. J. and Giachino, C., 2012. High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells. Stem Cells, 30 (7), pp. 1414-1423.


Bone, H. K., Nelson, A. S., Goldring, C. E., Tosh, D. and Welham, M. J., 2011. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. Journal of Cell Science, 124 (12), pp. 1992-2000.


Storm, M. P., Orchard, C. B., Bone, H. K., Chaudhuri, J. B. and Welham, M. J., 2010. Three-dimensional culture systems for the expansion of pluripotent embryonic stem cells. Biotechnology and Bioengineering, 107 (4), pp. 683-695.


Bone, H. K., Damiano, T., Bartlett, S., Perry, A., Letchford, J., Ripoli, Y. S., Nelson, A. S. and Welham, M. J., 2009. Involvement of GSK-3 in regulation of murine embryonic stem cell self-renewal revealed by a series of bisindolylmaleimides. Chemistry & Biology, 16 (1), pp. 15-27.

Martin-Fernandez, C., Bales, J., Hodgkinson, C., Welman, A., Welham, M. J., Dive, C. and Morrow, C. J., 2009. Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs. Molecular Cancer Research, 7 (6), pp. 955-965.

Schulz, H., Kolde, R., Adler, P., Aksoy, I., Anastassiadis, K., Bader, M., Billon, N., Boeuf, H., Bourillot, P., Buchholz, F., Dani, C., Doss, M. X., Forrester, L., Gitton, M., Henrique, D., Hescheler, J., Himmelbauer, H., Hübner, N., Karantzali, E., Kretsovali, A., Lubitz, S., Pradier, L., Rai, M., Reimand, J., Rolletschek, A., Sachinidis, A., Savatier, P., Stewart, F., Storm, M. P., Trouillas, M., Vilo, J., Welham, M. J., Winkler, J., Wobus, A. M., Hatzopoulos, A. K., Sham, M. H. and , T. F. C., 2009. The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS ONE, 4 (9), e6804.


Dobbin, E., Corrigan, P. M., Walsh, C. P., Welham, M. J., Freeburn, R. W. and Wheadon, H., 2008. Tel/PDGFR beta inhibits self-renewal and directs myelomonocytic differentiation of ES cells. Leukemia Research, 32 (10), pp. 1554-1564.


Dowden, J. and Welham, M., 2007. Reagents and Methods for Cross-Linking Biological Molecules. C07D207/46- WO2007113575 (A2), 11 October 2007.

Akasaka, T., Balasas, T., Russell, L. J., Sugimoto, K. J., Majid, A., Walewska, R., Karran, E. L., Brown, D. G., Cain, K., Harder, L., Gesk, S., Martin-Subero, J. I., Atherton, M. G., Brüggemann, M., Calasanz, M. J., Davies, T., Haas, O. A., Hagemeijer, A., Kempski, H., Lessard, M., Lillington, D. M., Moore, S., Nguyen-Khac, F., Radford-Weiss, I., Schoch, C., Struski, S., Talley, P., Welham, M. J., Worley, H., Strefford, J. C., Harrison, C. J., Siebert, R. and Dyer, M. J. S., 2007. Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood, 109 (8), pp. 3451-3461.

Foster, S. R., Pearce, A., Blake, A. J., Welham, M. J. and Dowden, J., 2007. Novel octavalent cross-linker displays efficient trapping of protein protein interactions. Chemical Communications

Bone, H. K. and Welham, M. J., 2007. Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis. Journal of Cell Science, 120 (10), pp. 1752-1762.

Welham, M. J., Storm, M. P., Kingham, E. and Bone, H. K., 2007. Phosphoinositide 3-kinases and regulation of embryonic stem cell fate. Biochemical Society Transactions, 35 (2), pp. 225-228.

Storm, M. P., Bone, H. K., Beck, C. G., Bourillot, P. Y., Schreiber, V., Damiano, T., Nelson, A., Savatier, P. and Welham, M. J., 2007. Regulation of Nanog expression by phophoinositide-3-kinase-dependent signalling in murine embryonic stem cells. Journal of Biological Chemistry, 282 (9), pp. 6265-6273.

Crabbe, T., Welham, M. and Ward, S., 2007. The PI3K inhibitor arsenal: choose your weapon! Trends in Biochemical Sciences, 32 (10), pp. 450-456.


Welham, M. J., 2006. Embryonic stem cells - past, present, future. The Biochemist, 28, pp. 25-28.

Letchford, J., Cardwell, A. M., Stewart, K., Coogans, K. K. S., Cox, J. P. L., Lee, M., Beresford, J. N., Perry, M. J. and Welham, M. J., 2006. Isolation of C15: A novel antibody generated against mesenchymal stem cell-enriched adult human marrow. Journal of Immunological Methods, 308 (1-2), pp. 124-137.

Edmead, C. E., Fox, B. C., Stace, C., Ktistakis, N. and Welham, M. J., 2006. The pleckstrin homology domain of Gab-2 is required for optimal interleukin-3 signalsome-mediated responses. Cellular Signalling, 18 (8), pp. 1147-1155.


Wright, K. L., Rooney, N., Feeney, M., Tate, J., Robertson, D., Welham, M. J. and Ward, S. G., 2005. Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing. Gastroenterology, 129 (2), pp. 437-453.


Paling, N. R. D., Wheadon, H., Bone, H. K. and Welham, M. J., 2004. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. Journal of Biological Chemistry, 279 (46), pp. 48063-48070.

Letchford, J., Cardwell, A., Lee, M., Beresford, J. N., Welham, M. J. and Perry, M. J., 2004. The generation of antibodies against adult human mesenchymal stem cells by phage display. Journal of Bone and Mineral Research, 19 (6), p. 1045.

Welham, M. J., 2004. VAP-1: a new anti-inflammatory target? Blood, 103 (9), pp. 3250-3251.


Ward, S. G., Finan, P. and Welham, M. J., 2003. P13K comes of age. Nature Immunology, 4 (1), p. 2.


Wheadon, H., Paling, N. R. D. and Welham, M. J., 2002. Molecular interactions of SHP1 and SHP2 in IL-3-signalling. Cellular Signalling, 14, pp. 219-229.


Patel, N., Craddock, B. L., Staniforth, J. N., Tobyn, M. J. and Welham, M. J., 2001. Spray-dried insulin particles retain biological activity in rapid in-vitro assay. Journal of Pharmacy and Pharmacology, 53, pp. 1415-1418.

This list was generated on Wed May 23 06:06:22 2018 IST.