Items by Caunt, Dr Christopher

2013

Pereira Morais, M. P., Marshall, D., Flower, S. E., Caunt, C. J., James, T. D., Williams, R. J., Waterfield, N. R. and Van Den Elsen, J. M. H., 2013. Analysis of protein glycation using fluorescent phenylboronate gel electrophoresis. Scientific Reports, 3, 1437.

Caunt, J., 2013. Dual-specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling. FEBS Journal, 280 (2), pp. 489-504.

2012

Finch, A. R., Caunt, C. J., Perrett, R. M., Tsaneva-Atanasova, K. and McArdle, C. A., 2012. Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases. Cellular Signalling, 24 (5), pp. 1002-1011.

Tsaneva-Atanasova, K., Mina, P., Caunt, C. J., Armstrong, S. P. and McArdle, C. A., 2012. Decoding GnRH neurohormone pulse frequency by convergent signalling modules. Journal of the Royal Society, Interface, 9 (66), pp. 170-182.

Caunt, C. J. and McArdle, C. A., 2012. ERK phosphorylation and nuclear accumulation: Insights from single-cell imaging. Biochemical Society Transactions, 40 (1), pp. 224-229.

Caunt, C.J., Perett, R.M., Fowkes, R.C. and McArdle, C.A., 2012. Mechanisms of GnRH-induced extracellular signal-regulated kinase nuclear localization. PLoS ONE, 7 (7), e40077.

2011

Dukes, J. D., Fish, L., Richardson, J. D., Blaikley, E., Burns, S., Caunt, C. J., Chalmers, A. D. and Whitley, P., 2011. Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells. Molecular Biology of the Cell, 22 (17), pp. 3192-3205.

Armstrong, S. P., Caunt, C. J., Finch, A. R. and McArdle, C. A., 2011. Using automated imaging to interrogate gonadotrophin-releasing hormone receptor trafficking and function. Molecular and Cellular Endocrinology, 331 (2), pp. 194-204.

2010

Caunt, C. J. and McArdle, C. A., 2010. Stimulus-induced uncoupling of extracellular signal-regulated kinase phosphorylation from nuclear localization is dependent on docking domain interactions. Journal of Cell Science, 123 (24), pp. 4310-4320.

Welsh, G. I., Hale, L. J., Eremina, V., Jeansson, M., Maezawa, Y., Lennon, R., Pons, D. A., Owen, R. J., Satchell, S. C., Miles, M. J., Caunt, C. J., McArdle, C. A., Pavenstädt, H., Tavaré, J. M., Herzenberg, A. M., Kahn, C. R., Mathieson, P. W., Quaggin, S. E., Saleem, M. A. and Coward, R. J. M., 2010. Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metabolism, 12 (4), pp. 329-340.

Armstrong, S. P., Caunt, C. J., Fowkes, R. C., Tsaneva-Atanasova, K. and McArdle, C. A., 2010. Pulsatile and sustained Gonadotropin-releasing Hormone (GnRH) receptor signaling: Does the ERK signaling pathway decode GnRH pulse frequencey? Journal of Biological Chemistry, 285 (32), pp. 24360-24371.

Finch, A. R., Caunt, C. J., Armstrong, S. P. and McArdle, C. A., 2010. Plasma membrane expression of Gonadotropin-Releasing Hormone receptors: regulation by peptide and nonpeptide antagonists. Molecular Endocrinology, 24 (2), pp. 423-435.

Finch, A. R., Sedgley, K. R., Armstrong, S. P., Caunt, C. J. and McArdle, C. A., 2010. Trafficking and signalling of gonadotrophin-releasing hormone receptors: an automated imaging approach. British Journal of Pharmacology, 159 (4), pp. 751-760.

Caunt, C. J., Armstrong, S. P. and McArdle, C. A., 2010. Using high-content microscopy to study gonadotrophin-releasing hormone regulation of ERK. Methods in Molecular Biology, 661 (6), pp. 507-524.

2009

Bailey, C. P., Oldfield, S., Llorente, J., Caunt, C. J., Teschemacher, A., Roberts, L., McArdle, C., Smith, F., Dewey, W., Kelly, E. and Henderson, G., 2009. Involvement of PKCα and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of µ-opioid receptors in mature brain neurons. British Journal of Pharmacology, 158 (1), pp. 157-164.

Finch, A. R., Caunt, C. J., Armstrong, S. P. and McArdle, C. A., 2009. Agonist-induced internalization and downregulation of gonadotropin-releasing hormone receptors. American Journal of Physiology - Cell Physiology, 297 (3), C591-C600.

Armstrong, S. P., Caunt, C. J. and McArdle, C. A., 2009. Gonadotropin-Releasing Hormone and protein kinase C signaling to ERK: spatiotemporal regulation of ERK by docking domains and dual-specificity phosphatases. Molecular Endocrinology, 23 (4), pp. 510-519.

Maru, B., Tobias, J., Rivers, C., Caunt, C., Norman, M. and McArdle, C., 2009. Potential use of an estrogen–glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity. Bone, 44 (1), pp. 102-112.

Armstrong, S. P., Caunt, C. J., Fowkes, R. C., Tsaneva-Atanasova, K. and McArdle, C. A., 2009. Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling: does the Ca2+/NFAT signaling pathway decode GnRH pulse frequency? Journal of Biological Chemistry, 284 (51), pp. 35746-35757.

2008

Caunt, C. J., Armstrong, S. P., Rivers, C. A., Norman, M. R. and McArdle, C. A., 2008. Spatiotemporal regulation of ERK2 by dual specificity phosphatases. Journal of Biological Chemistry, 283 (39), pp. 26612-26623.

Caunt, C. J., Rivers, C. A., Conway-Campbell, B. L., Norman, M. R. and McArdle, C. A., 2008. Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases. Journal of Biological Chemistry, 283 (10), pp. 6241-6252.

Finch, A. R., Sedgley, K. R., Caunt, C. J. and McArdle, C. A., 2008. Plasma membrane expression of GnRH receptors: regulation by antagonists in breast, prostate, and gonadotrope cell lines. The Journal of Endocrinology, 196 (2), pp. 353-367.

2006

Sedgley, K. R., Finch, A. R., Caunt, C. J. and McArdle, C. A., 2006. Intracellular gonadotropin-releasing hormone receptors in breast cancer and gonadotrope lineage cells. Journal of Endocrinology, 191 (3), pp. 625-836.

Caunt, C. J., Finch, A. R., Sedgley, K. R. and McArdle, C. A., 2006. GnRH receptor signalling to ERK: kinetics and compartmentalization. Trends in Endocrinology and Metabolism, 17 (8), pp. 308-313.

Caunt, C. J., Finch, A. R., Sedgley, K. R., Oakley, L., Luttrell, L. M. and McArdle, C. A., 2006. Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors - Receptor-specific activation mechanisms and compartmentalization. Journal of Biological Chemistry, 281 (5), pp. 2701-2710.

Caunt, C. J., Finch, A. R., Sedgley, K. R. and McArdle, C. A., 2006. Seven-transmembrane receptor signalling and ERK compartmentalization. Trends in Endocrinology and Metabolism, 17 (7), pp. 276-283.

2005

Hislop, J. N., Caunt, C. J., Sedgley, K. R., Kelly, E., Mundell, S., Green, L. D. and McArdle, C. A., 2005. Internalization of gonadotropin-releasing hormone receptors (GnRHRs): does arrestin binding to the C-terminal tail target GnRHRs for dynamin-dependent internalization? Journal of Molecular Endocrinology, 35 (1), pp. 177-189.

2004

Kiss-Toth, E., Bagstaff, S. M., Sung, H. Y., Jozsa, V., Dempsey, C., Caunt, J. C., Oxley, K. M., Wyllie, D. H., Polgar, T., Harte, M., O'Neill, L. A. J., Qwarnstrom, E. E. and Dower, S. K., 2004. Human Tribbles, a Protein Family Controlling Mitogen-activated Protein Kinase Cascades. Journal of Biological Chemistry, 279 (41), pp. 42703-42708.

Caunt, C. J., Hislop, J. N., Kelly, E., Matharu, A. L., Green, L. D., Sedgley, K. R., Finch, A. R. and McArdle, C. A., 2004. Regulation of gonadotropin-releasing hormone receptors by protein kinase C: Inside out signalling and evidence for multiple active conformations. Endocrinology, 145 (8), pp. 3594-3602.

2002

Valles, S., Caunt, C. J., Walker, M. H. and Qwarnstrom, E. E., 2002. PDGF enhancement of IL-1 receptor levels in smooth muscle cells involves induction of an attachment-regulated, heparan sulfate binding site (IL-1RIII). Laboratory Investigation: A Journal of Technical Methods and Pathology, 82 (7), pp. 855-862.

2001

Caunt, C. J., Kiss-Toth, E., Carlotti, F., Chapman, R. and Qwarnstrom, E. E., 2001. Ras controls tumor necrosis factor receptor-associated factor (TRAF)6-dependent induction of nuclear factor-kappa B - Selective regulation through receptor signaling components. Journal of Biological Chemistry, 276 (9), pp. 6280-6288.