Research

Items by Price, Robert

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Number of items: 77.

Book Sections

Shur, J. and Price, R., 2011. The influence of crystals, particles and powders on the performance of dry powder inhalers. In: 2011 AIChE Annual Meeting, Conference Proceedings. AIChE.

Articles

Kinnunen, H., Hebbink, G., Peters, H., Shur, J. and Price, R., 2014. An Investigation into the Effect of Fine Lactose Particles on the Fluidization Behaviour and Aerosolization Performance of Carrier-Based Dry Powder Inhaler Formulations. AAPS PharmSciTech, 15 (4), pp. 898-909.

Kinnunen, H., Hebbink, G., Peters, H., Shur, J. and Price, R., 2014. Defining the critical material attributes of lactose monohydrate in carrier based dry powder inhaler formulations using artificial neural networks. AAPS PharmSciTech, 15 (4), pp. 1009-1020.

Tomaszewska, I., Karki, S., Shur, J., Price, R. and Fotaki, N., 2013. Pharmaceutical characterisation and evaluation of cocrystals : importance of in vitro dissolution conditions and type of coformer. International Journal of Pharmaceutics, 453 (2), pp. 380-388.

Shur, J., Pitchayajittipong, C., Rogueda, P. and Price, R., 2013. Effect of processing history on the surface interfacial properties of budesonide in carrier-based dry-powder inhalers. Therapeutic Delivery, 4 (8), pp. 925-937.

Shur, J., Lee, S., Adams, W., Lionberger, R., Tibbatts, J. and Price, R., 2012. Effect of device design on the in vitro performance and comparability for capsule-based dry powder inhalers. AAPS Journal, 14 (4), pp. 667-676.

Shur, J., Kubavat, H. A., Ruecroft, G., Hipkiss, D. and Price, R., 2012. Influence of crystal form of ipratropium bromide on micronisation and aerosolisation behaviour in dry powder inhaler formulations. Journal of Pharmacy and Pharmacology, 64 (9), pp. 1326-1336.

Kubavat, H. A., Shur, J., Ruecroft, G., Hipkiss, D. and Price, R., 2012. Influence of primary crystallisation conditions on the mechanical and interfacial properties of micronised budesonide for dry powder inhalation. International Journal of Pharmaceutics, 430 (1-2), pp. 26-33.

Kubavat, H. A., Shur, J., Ruecroft, G., Hipkiss, D. and Price, R., 2012. Investigation into the influence of primary crystallization conditions on the mechanical properties and secondary processing behaviour of fluticasone propionate for carrier based dry powder inhaler formulations. Pharmaceutical Research, 29 (4), pp. 994-1006.

Shur, J. and Price, R., 2012. Advanced microscopy techniques to assess solid-state properties of inhalation medicines. Advanced Drug Delivery Reviews, 64 (4), pp. 369-382.

de Boer, A. H., Chan, H. K. and Price, R., 2012. A critical view on lactose-based drug formulation and device studies for dry powder inhalation: Which are relevant and what interactions to expect? Advanced Drug Delivery Reviews, 64 (3), pp. 257-274.

Rogueda, P. G. A., Price, R., Smith, T., Young, P. M. and Traini, D., 2011. Particle synergy and aerosol performance in non-aqueous liquid of two combinations metered dose inhalation formulations: An AFM and Raman investigation. Journal of Colloid and Interface Science, 361 (2), pp. 649-655.

Ireland, A. J., Wilson, A. A., Blythe, L., Johnston, N. J., Price, R. and Sandy, J. R., 2011. Particulate production during orthodontic production laboratory procedures. Journal of Exposure Science and Environmental Epidemiology, 21 (5), pp. 536-540.

Kinnunen, H., Shur, J., Hebbink, G., Muresan, A. S. and Price, R., 2010. Lactose fluidisation properties and their relationship to dry powder inhaler performance. Journal of Pharmacy and Pharmacology, 62 (10), pp. 1342-1343.

Pitchayajittipong, C., Price, R., Shur, J., Kaerger, J. S. and Edge, S., 2010. Characterisation and functionality of inhalation anhydrous lactose. International Journal of Pharmaceutics, 390 (2), pp. 134-141.

Pitchayajittipong, C., Shur, J. and Price, R., 2009. Engineering of crystalline combination inhalation particles of a long-acting β2-agonist and a corticosteroid. Pharmaceutical Research, 26 (12), pp. 2657-2666.

Begat, P., Morton, D. A. V., Shur, J., Kippax, P., Staniforth, J. N. and Price, R., 2009. The role of force control agents in high-dose dry powder inhaler formulations. Journal of Pharmaceutical Sciences, 98 (8), pp. 2770-2783.

Shur, J., Harris, H., Jones, M. D., Kaerger, J. S. and Price, R., 2008. The role of fines in the modification of the fluidization and dispersion mechanism within dry powder inhaler formulations. Pharmaceutical Research, 25 (7), pp. 1631-1640.

Jones, M. D., Harris, H., Hooton, J. C., Shur, J., King, G. S., Mathoulin, C. A., Nichol, K., Smith, T. L., Dawson, M. L., Ferrie, A. R. and Price, R., 2008. An investigation into the relationship between carrier-based dry powder inhalation performance and formulation cohesive-adhesive force balances. European Journal of Pharmaceutics and Biopharmaceutics, 69 (2), pp. 496-507.

Jones, M. D., Hooton, J. C., Dawson, M. L., Ferrie, A. R. and Price, R., 2008. An investigation into the dispersion mechanisms of ternary dry powder inhaler formulations by the quantification of interparticulate forces. Pharmaceutical Research, 25 (2), pp. 337-348.

Young, P. M. and Price, R., 2008. Comparative measurements of pressurised metered dose inhaler (pMDI) stem displacement. Drug Development and Industrial Pharmacy, 34 (1), pp. 90-94.

Tuley, R., Shrimpton, J., Jones, M. D., Price, R., Palmer, M. and Prime, D., 2008. Experimental observations of dry powder inhaler dose fluidisation. International Journal of Pharmaceutics, 358 (1-2), pp. 238-247.

Day, C. J., Price, R., Sandy, J. R. and Ireland, A. J., 2008. Inhalation of aerosols produced during the removal of fixed orthodontic appliances: A comparison of 4 enamel cleanup methods. American Journal of Orthodontics and Dentofacial Orthopedics, 133 (1).

Jones, M. D., Young, P. M., Traini, D., Shur, J., Edge, S. and Price, R., 2008. The use of atomic force microscopy to study the conditioning of micronised budesonide. International Journal of Pharmaceutics, 357 (1-2), pp. 314-317.

Gomez, G. R., Fernandez, I., Ortiz, F. L., Price, R. D., Davidson, M. G., Mahon, M. F. and Howard, J. A. K., 2007. A tetrameric lithiated phosphazene containing a lithium atom bound exclusively to four sp(3)-hybridized carbanionic centers: A key intermediate for understanding structure-reactivity relationships of phosphazenyllithium compounds. Organometallics, 26 (3), pp. 514-518.

Young, P. M., Edge, S., Staniforth, J. N., Steele, D. F., Traini, D. and Price, R., 2007. Effect of moisture on the compressibility and compactibility of sodium starch glycolate. Pharmaceutical Development and Technology, 12 (2), pp. 217-222.

Traini, D., Young, P. M., Rogueda, P. and Price, R., 2007. In vitro investigation of drug particulates interactions and aerosol performance of pressurised metered dose inhalers. Pharmaceutical Research, 24 (1), pp. 125-135.

Young, P. M., Edge, S., Staniforth, J. N., Steele, D. F. and Price, R., 2007. Interaction of moisture with sodium starch glycolate. Pharmaceutical Development and Technology, 12 (2), pp. 211-216.

Traini, D., Young, P. M., Price, R. and Rogueda, P., 2006. A novel apparatus for the determination of solubility in pressurized metered dose inhalers. Drug Development and Industrial Pharmacy, 32 Nov-Dec (10), pp. 1159-1163.

Shur, J., Kaerger, J. S. and Price, R., 2006. Characterisation of the surface physico-mechanical properties of an active pharmaceutical ingredient by atomic force microscopy. Journal of Pharmacy and Pharmacology, 58, A73-A74.

Traini, D., Young, P. M., Jones, M., Edge, S. and Price, R., 2006. Comparative study of erythritol and lactose monohydrate as carriers for inhalation: atomic force microscopy and in vitro correlation. European Journal of Pharmaceutical Sciences, 27, pp. 243-251.

El-Sabawi, D., Edge, S., Price, R. and Young, P. M., 2006. Continued investigation into the influence of loaded dose on the performance of dry powder inhalers: Surface smoothing effects. Drug Development and Industrial Pharmacy, 32 Nov-Dec (10), pp. 1135-1138.

Jones, M. D., Hooton, J. C., Dawson, M. L., Ferrie, A. R. and Price, R., 2006. Dehydration of trehalose dihydrate at low relative humidity and ambient temperature. International Journal of Pharmaceutics, 313 (1-2), pp. 87-98.

Traini, D., Young, P. M., Rogueda, P. and Price, R., 2006. Investigation into the influence of polymeric stabilizing excipients on inter-particulate forces in pressurised metered dose inhalers. International Journal of Pharmaceutics, 320 (1-2), pp. 58-63.

El-Sabawi, D., Price, R., Edge, S. and Young, P. M., 2006. Novel temperature controlled surface dissolution of excipient particles for carrier based dry powder inhaler formulations. Drug Development and Industrial Pharmacy, 32 (2), pp. 243-251.

Hooton, J. C., Jones, M. D. and Price, R., 2006. Predicting the behavior of novel sugar carriers for dry powder inhaler formulations via the use of a cohesive-adhesive force balance approach. Journal of Pharmaceutical Sciences, 95 (6), pp. 1288-1297.

Pitchayajittipong, C., Shur, J. and Price, R., 2006. The generation of spherical crystalline particles via a novel particle engineering process. Journal of Pharmacy and Pharmacology, 58, A76-A77.

Jones, M. D. and Price, R., 2006. The influence of fine excipient particles on the performance of carrier-based dry powder inhalation formulations. Pharmaceutical Research, 23 (8), pp. 1665-1674.

Bouissou, C., Rouse, J. J., Price, R. and van der Walle, C. F., 2006. The influence of surfactant on PLGA microsphere glass transition and water sorption: Remodeling the surface morphology to attenuate the burst release. Pharmaceutical Research, 23 (6), pp. 1295-1305.

Traini, D., Young, P. M., Rogueda, P. and Price, R., 2006. The use of AFM and surface energy measurements to investigate drug-canister material interactions in a model pressurized metered dose inhaler formulation. Aerosol Science and Technology, 40 (4), pp. 227-236.

Jones, M. D., Hooton, J. C., Dawson, M. L., Ferrie, A. R. and Price, R., 2006. The use of AFM to investigate how fines improve DPI performance. Journal of Pharmacy and Pharmacology, 58, A42-A43.

Young, P. M., Tobyn, M. J., Price, R., Buttrum, M. and Dey, F., 2006. The use of colloid probe microscopy to predict aerosolization performance in dry powder inhalers: AFM and in vitro correlation. Journal of Pharmaceutical Sciences, 95 (8), pp. 1800-1809.

Young, P. M., Edge, S., Staniforth, J. N., Steele, D. F. and Price, R., 2005. Dynamic vapor sorption properties of sodium starch glycolate disintegrants. Pharmaceutical Development and Technology, 10 (2), pp. 249-259.

McLoughlin, M. J., Mays, T. J. and Price, R., 2005. Growth spiral activity and step velocities on a crystal surface. Physical Review Letters, 95 (11), 115504-1-115504-4.

Price, R. and Young, P. M., 2005. On the physical transformations of processed pharmaceutical solids. Micron, 36, pp. 519-524.

Bouissou, C., Begat, P., van der Walle, C. and Price, R., 2005. Study of the surface mobility of PLGA microspheres using high-resolution topography measurements with the atomic force microscope. Journal of Controlled Release, 101 (1-3), pp. 290-292.

Traini, D., Rogueda, P., Young, P. and Price, R., 2005. Surface energy and interparticle forces correlations in model pMDI formulations. Pharmaceutical Research, 22 (5), pp. 816-825.

Young, P. M., Edge, S., Traini, D., Jones, M. D., Price, R., El-Sabawi, D., Urry, C. and Smith, C., 2005. The influence of dose on the performance of dry powder inhalation systems. International Journal of Pharmaceutics, 296, pp. 26-33.

Ferrari, F., Cocconi, D., Bettini, R., Giordano, F., Santi, P., Tobyn, M., Price, R., Young, P., Caramella, C. and Colombo, P., 2004. The surface roughness of lactose particles can be modulated by wet-smoothing using a high-shear mixer. AAPS PharmSciTech, 5 (4), pp. 69-74.

Begat, P., Morton, D. A. V., Staniforth, J. N. and Price, R., 2004. The cohesive-adhesive balances in dry powder inhaler formulations I: direct quantification by atomic force microscopy. Pharmaceutical Research, 21 (9), pp. 1591-1597.

Kaerger, J. S., Edge, S. and Price, R., 2004. Influence of particle size and shape on flowability and compactibility of binary mixtures of paracetamol and microcrystalline cellulose. European Journal of Pharmaceutical Sciences, 22 (2-3), pp. 173-179.

Kaerger, J. S. and Price, R., 2004. Processing of spherical crystalline particles via a novel solution atomization and crystallization by sonication (SAXS) technique. Pharmaceutical Research, 21 (2), pp. 372-381.

Parker, C. A., Anderson, N. J., Robinson, E. S. J., Price, R., Tyacke, R. J., Husbands, S. M., Dillon, M. P., Eglen, R. M., Hudson, A. L., Nutt, D. J., Crump, M. P. and Crosby, J., 2004. Harmane and harmalan are bioactive components of classical clonidine-displacing substance. Biochemistry, 43, pp. 16385-16392.

Kusmartseva, O., Kattige, A. S., Price, R. and Smith, P. R., 2004. In-line assessment of pulmonary drug delivery using light obscuration. Biosensors and Bioelectronics, 20, pp. 468-474.

Begat, P., Morton, D. A. V., Staniforth, J. N. and Price, R., 2004. The cohesive-adhesive balances in dry powder inhaler formulations II: Influence on fine particle delivery characteristics. Pharmaceutical Research, 21 (10), pp. 1826-1833.

Young, P. M., Thompson, J., Woodcock, D., Aydin, M. and Price, R., 2004. The development of a novel high-dose pressurized aerosol dry-powder device (PADD) for the deliverv of pumactant for inhalation therapy. Journal of Aerosol Medicine-Deposition Clearance and Effects in the Lung, 17 Sum (2), pp. 123-128.

Price, R. D., Fernandez, I., Gomez, G. R., Ortiz, F. L., Davidson, M. G., Cowan, J. A. and Howard, J. A. K., 2004. The first mixed-anion complex of a lithium phosphazene: Synthesis and crystal and solution structure of [(LiCH2P(Ph)(2)=NPh)center dot(LiOC6H2-2,6-{C(CH3)(3)}-4-CH3)](2). Organometallics, 23 (25), pp. 5934-5938.

Young, P. M. and Price, R., 2004. The influence of humidity on the aerosolisation of micronised and SEDS produced salbutamol sulphate. European Journal of Pharmaceutical Sciences, 22, pp. 235-240.

Young, P. M., Price, R., Tobyn, M. J., Buttrum, M. and Dey, F., 2004. The influence of relative humidity on the cohesion properties of micronized drugs used in inhalation therapy. Journal of Pharmaceutical Sciences, 93 (3), pp. 753-761.

Steele, D. F., Young, P. M., Price, R., Smith, T., Edge, S. and Lewis, D., 2004. The potential use of raman mapping to investigate in vitro deposition of combination pressurized metered-dose inhalers. AAPS Journal, 6 (4), 32.

Price, R. and Young, P. M., 2004. Visualization of the crystallization of lactose from the amorphous state. Journal of Pharmaceutical Sciences, 93 (1), pp. 155-164.

Fernandez, I., Price, R. D., Bolton, P. D., Mahon, M. F., Davidson, M. G. and Lopez-Ortiz, F., 2004. X-ray and multinuclear NMR study of the mixed aggregate [(Ph2P(O)N(CH2Ph)CH3) · LiOC6H2-2,6-{C(CH3)3}2-4-CH3) · C7H8]2: a model for the directed metalation of phosphinamides. Journal of Organometallic Chemistry, 689 (11), pp. 1890-1896.

Ireland, A. J., Moreno, T. and Price, R., 2003. Airborne particles produced during enamel cleanup after removal of orthodontic appliances. American Journal of Orthodontics and Dentofacial Orthopedics, 124, pp. 683-686.

Young, P. M., Price, R., Tobyn, M. J., Buttrum, M. and Dey, F., 2003. Effect of humidity on aerosolization of micronized drugs. Drug Development and Industrial Pharmacy, 29 (9), pp. 959-966.

Young, P. M., Booth, J., Price, R. and Tobyn, M. J., 2003. Environmentally controlled optical microscopy for the pharmaceutical sciences. Environ.Microscopy, 95, pp. 5-7.

Young, P. M., Price, R., Tobyn, M. J., Buttrum, M. and Dey, F., 2003. Investigation into the effect of humidity on drug-drug interactions using the atomic force microscope. Journal of Pharmaceutical Sciences, 92 (4), pp. 815-822.

Begat, P., Young, P. M., Edge, S., Kaerger, J. S. and Price, R., 2003. The effect of mechanical processing on surface stability of pharmaceutical powders: Visualization by atomic force microscopy. Journal of Pharmaceutical Sciences, 92 (3), pp. 611-620.

Young, P. M., Price, R., Tobyn, M. J., Buttrum, M. and Dey, F., 2003. The influence of relative humidity on the cohesion properties of micronised drugs used in inhalation therapy. Journal of Pharmaceutical Sciences, 93, pp. 753-761.

Young, P. M., Price, R., Lewis, D., Edge, S. and Traini, D., 2003. Under pressure: predicting pressurized metered dose inhaler interactions using the atomic force microscope. Journal of Colloid and Interface Science, 262, pp. 298-302.

Price, R. and Young, P. M., 2003. Visualisation of the crystallisation of lactose from the amorphous state. Journal of Pharmaceutical Sciences, 93 (1), pp. 155-164.

Young, P. M., Cocconi, D., Colombo, P., Bettini, R., Price, R., Steele, D. F. and Tobyn, M. J., 2002. Characterization of a surface modified dry powder inhalation carrier prepared by "particle smoothing". Journal of Pharmacy and Pharmacology, 54, pp. 1339-1344.

Edge, S., Belu, A. M., Potter, U. J., Steele, D. F., Young, P. M., Price, R. and Staniforth, J. N., 2002. Chemical characterisation of sodium starch glycolate particles. International Journal of Pharmaceutics, 240, pp. 67-78.

Price, R., Young, P. M., Edge, S. and Staniforth, J. N., 2002. The influence of relative humidity on particulate interactions in carrier-based dry powder inhaler formulations. International Journal of Pharmaceutics, 246 (1-2), pp. 47-59.

Ahrens, B., Davidson, M. G., Forsyth, V. T., Mahon, M. F., Johnson, A. L., Mason, S. A., Price, R. D. and Raithby, P. R., 2001. Neutron diffraction study of a phenol-nitroxide radical adduct: A structural model for hydrogen atom abstraction by peroxyl radicals from vitamin E and related phenolic antioxidants. Journal of the American Chemical Society, 123 (37), pp. 9164-9165.

Conference or Workshop Items

Fotaki, N., Box, K., Comer, J., Mole, J., Taylor, R., Karki, S. and Price, R., 2013. Dissolution and precipitation studies of carbamazepine cocrystals with small scale assays. In: 2013 AAPS Annual Meeting and Exposition, 2013-11-10 - 2013-11-14, San Antonio.

Patent

Price, R. and Kaerger, J. S., 2005. Process for the Production of Particles. A61K9/16-NO20053796 (A), 03 November 2005.

Price, R., 2003. Process for the Treatment of Particles for Use in Pharmaceutical Formulations. A61K9/00-WO03094883 (A2), 20 November 2003.

This list was generated on Thu Sep 18 21:12:29 2014 IST.