Research

Items by Pourzand, Charareh

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Number of items: 38.

Book Sections

Blagbrough, I. S., Adjimatera, N., Ahmed, O. A. A., Neal, A. P. and Pourzand, C. A., 2004. Spermine and lipopolyamines as gene delivery agents. In: Beadle, D. J., Mellor, I. R. and Usherwood, P. N. R., eds. Neurotox '03: Neurotoxicological targets from Functional Genomics and Proteomics. Society of Chemical Industry, pp. 147-159. (Functional Genomics and Proteomics)

Pourzand, C., Reelfs, O. and Tyrrell, R., 2000. Approaches to define the involvement of reactive oxygen species and iron in Ultraviolet-A inducible gene expression. In: Walker, J. M. and Keyse, S. M., eds. Stress Response: Methods and Protocols. Vol. 99. Springer, pp. 257-276. (Methods in Molecular Biology)

Pourzand, C., Reelfs, O. and Tyrrell, R., 2000. Heme oxygenase activity current methods and applications. In: Walker, J. M. and Keyse, S. M., eds. Stress Response: Methods and Protocols. Vol. 99. Humana Press, pp. 369-391. (Methods in Molecular Biology)

Articles

Al-Qenaei, A., Yiakouvaki, A., Reelfs, O., Santambrogio, P., Levi, S., Hall, N. D., Tyrrell, R. M. and Pourzand, C., 2014. Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide. Free Radical Biology and Medicine, 68, pp. 87-100.

Metwally, A. A., Reelfs, O., Pourzand, C. and Blagbrough, I. S., 2012. Efficient silencing of EGFP reporter gene with siRNA delivered by asymmetrical N4,N9-diacyl spermines. Molecular Pharmaceutics, 9 (7), pp. 1862-1876.

Aroun, A., Zhong, J. L., Tyrrell, R. M. and Pourzand, C., 2012. Iron, oxidative stress and the example of solar ultraviolet A radiation. Photochemical & Photobiological Sciences, 11 (1), pp. 118-134.

Metwally, A. A., Reelfs, O., Pourzand, C. and Blagbrough, I. S., 2011. Asymmetrical N4,N9-diacyl spermines: SAR and their efficiency as siRNA delivery vectors compared with symmetrical mixtures. Human Gene Therapy, 22 (10), A84-A85.

Pelle, E., Jian, J. L., Declercq, L., Dong, K., Yang, Q., Pourzand, C., Maes, D., Pernodet, N., Yarosh, D. B. and Huang, X., 2011. Protection against ultraviolet A-induced oxidative damage in normal human epidermal keratinocytes under post-menopausal conditions by an ultraviolet A-activated caged-iron chelator: a pilot study. Photodermatology Photoimmunology & Photomedicine, 27 (5), pp. 231-235.

Metwally, A. A., Pourzand, C. and Blagbrough, I. A., 2011. Efficient gene silencing by self-assembled complexes of siRNA and symmetrical fatty acid amides of spermine. Pharmaceutics, 3 (2), pp. 125-140.

Metwally, A. A., Pourzand, C. and Blagbrough, I. S., 2010. Efficient siRNA delivery and effective gene silencing by lipoplexes. Drug Discovery Today, 15 (23-24), p. 1090.

Metwally, A. A., Pourzand, C. and Blagbrough, I. S., 2010. Efficient siRNA delivery and gene silencing by unsymmetrical fatty acid amides of spermine. Journal of Pharmacy and Pharmacology, 62 (10), pp. 1220-1221.

Ghonaim, H. M., Cheng, Y. X., Pourzand, C. and Blagbrough, I., 2010. Self-assembled complex formulations of lipid-aminoglycoside conjugates : Nanoparticles for efficient gene and siRNA delivery. Journal of Pharmacy and Pharmacology, 62 (10), pp. 1295-1296.

Reelfs, O., Eggleston, I. M. and Pourzand, C., 2010. Skin protection against UVA-induced iron damage by multiantioxidants and iron chelating drugs/prodrugs. Current Drug Metabolism, 11 (3), pp. 242-249.

Ghonaim, H. M., Ahmed, O. A. A., Pourzand, C. and Blagbrough, I. S., 2008. Varying the chain length in N4,N9-diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA formulation. Molecular Pharmaceutics, 5 (6), pp. 1111-1121.

Mecklenburg, S., Collins, C. A., Doring, M., Burkholz, T., Abbas, M., Fry, F. H., Pourzand, C. and Jacob, C., 2008. The design of multifunctional antioxidants against the damaging ingredients of oxidative stress. Phosphorus Sulfur and Silicon and the Related Elements, 183 (4), pp. 863-888.

Pourzand, C., Yiakouvaki, A., Savovi, J., Al-Qenaei, A. and Dowden, J., 2007. Caged-iron chelatrs' as powerful prodrugs to protect the skin cells against iron-mediated lysosomal damage and necrotic cell death. American Journal of Hematology, 82 (6), pp. 540-541.

Ghonaim, H. M., Li, S., Soltan, M. K., Pourzand, C. and Blagbrough, I. S., 2007. Chain length modulation in symmetrical lipopolyamines and the effect on nanoparticle formulations for gene delivery. Journal of Pharmacy and Pharmacology, 59, A36-A36.

Ghonaim, H. M., Li, S., Pourzand, C. and Blagbrough, I. S., 2007. Efficient novel unsymmetrical lipopolyamine formulations for gene delivery. Journal of Pharmacy and Pharmacology, 59, A37-A37.

Ghonaim, H. M., Li, S., Pourzand, C. and Blagbrough, I. S., 2007. Formulation and delivery of fluorescent siRNA by lipospermine nanoparticle complex formation. Journal of Pharmacy and Pharmacology, 59, A36-A37.

Al-Qenaei, A., Yiakouvaki, A., Hall, N. D. and Pourzand, C., 2007. The role of lysosomal labile iron pool in differential sensitivity of Jurkat T cell lines to hydrogen peroxide. American Journal of Hematology, 82 (6), p. 565.

Yiakouvaki, A., Savovic, J., Al-Qenaei, A., Dowden, J. and Pourzand, C. A., 2006. Caged-iron chelators a novel approach towards protecting skin cells against ultraviolet A-induced necrotic cell death. Journal Of Investigative Dermatology, 2006 (Epub ahead of print).

Ghonaim, H. M., Li, S., Pourzand, C. and Blagbrough, I. S., 2006. Design of lipospermine non-viral gene delivery vectors for self-assembly DNA nanoparticle formulations. Journal of Pharmacy and Pharmacology, 58, A7-A7.

Basu-Modak, S., Ali, D., Gordon, M., Polte, T., Yiakouvaki, A., Pourzand, C., Rice-Evans, C. and Tyrrell, R. M., 2006. Suppression of UVA-mediated release of labile iron by epicatechin - A link to lysosomal protection. Free Radical Biology and Medicine, 41 (8), pp. 1197-1204.

Ahmed, O. A. A., Pourzand, C. and Blagbrough, I. S., 2006. Varying the unsaturation in N4,N9-dioctadecanoyl spermines: Nonviral lipopolyamine vectors for more efficient plasmid DNA formulation. Pharmaceutical Research, 23 (1), pp. 31-40.

Adjimatera, N., Neal, A. P., Pourzand, C. and Blagbrough, I. S., 2005. Fluorescent lipopolyamines: A new class of molecular probes in non-viral gene therapy. Abstracts of Papers of the American Chemical Society, 229, U117-U117.

Adjimatera, N., Blagbrough, I. S. and Pourzand, C., 2005. Monitoring formulation and intracellular delivery of plasmids by lipopolyamines. Abstracts of Papers of the American Chemical Society, 229, U211-U211.

Ahmed, O. A. A., Adjimatera, N., Pourzand, C. and Blagbrough, I. S., 2005. N4,N9-dioleoyl spermine is a novel nonviral lipopolyamine vector for plasmid DNA formulation. Pharmaceutical Research, 22 (6), pp. 972-980.

Adjimatera, N., Pourzand, C. and Blagbrough, I. S., 2005. Synthesis and biological testing of lipopolyamine N2,N3-dioleoylspermine: Self-assembly of a nanopharmaceutical for plasmid delivery. Abstracts of Papers of the American Chemical Society, 229, U234-U234.

Collins, C. A., Fry, F. H., Holme, A. L., Yiakouvaki, A., Al-Qenaei, A., Pourzand, C. A. and Jacob, C., 2005. Towards multifunctional antioxidants: synthesis, electrochemistry, in vitro and cell culture evaluation of compounds with ligand/catalytic properties. Organic and Biomolecular Chemistry, 3, pp. 1541-1546.

Zhong, J. L., Holley, P., Tyrrell, R. M. and Pourzand, C. A., 2004. Susceptibility of skin cells to UVA-induced necrotic cell death reflects the intracellular level of labile iron. Journal Of Investigative Dermatology, 123, pp. 771-780.

Reelfs, O., Tyrrell, R. M. and Pourzand, C., 2004. Ultraviolet A radiation-induced immediate iron release is a key modulator of the activation of NF-kappa B in human skin fibroblasts. Journal Of Investigative Dermatology, 122 (6), pp. 1440-1447.

Tyrrell, R. M., Pourzand, C. A., Brown, J., Hejmadi, V., Kvam, E., Ryter, S. and Watkin, R. D., 2000. Cellular studies with UVA radiation: A role for iron. Radiation Protection Dosimetry, 91 (1-3), pp. 37-39.

Kvam, E., Hejmadi, V., Ryter, S., Pourzand, C. and Tyrrell, R. M., 2000. Heme oxygenase activity causes transient hypersensitivity to oxidative ultraviolet A radiation that depends on release of iron from heme. Free Radical Biology and Medicine, 28 (8), pp. 1191-1196.

Pourzand, C. and Tyrrell, R. M., 1999. Apoptosis, the role of oxidative stress and the example of solar UV radiation. Photochemistry and Photobiology, 70 (4), pp. 380-390.

Pourzand, C., Reelfs, O., Kvam, E. and Tyrrell, R. M., 1999. The iron regulatory protein can determine the effectiveness of 5-aminolevulinic acid in inducing protoporphyrin IX in human primary skin fibroblasts. Journal Of Investigative Dermatology, 112 (4), pp. 419-425.

Pourzand, C., Watkin, R. D., Brown, J. E. and Tyrrell, R. M., 1999. Ultraviolet A radiation induces immediate release of iron in human primary skin fibroblasts: The role of ferritin. Proceedings of the National Academy of Sciences of the United States of America, 96 (12), pp. 6751-6756.

Pourzand, C., Rossier, G., Reelfs, O., Borner, C. and Tyrrell, R. M., 1997. The overexpression of Bcl-2 inhibits UVA-mediated immediate apoptosis in rat 6 fibroblasts: Evidence for the involvement of Bcl-2 as an antioxidant. Cancer Research, 57 (8), pp. 1405-1411.

Conference or Workshop Items

Abbate, V., Hider, R. C., Pourzand, C. and Reelfs, O., 2013. Mitochondia-targeted iron chelators for the monitoring and adjustment of cellular labile iron pools. In: Fifth Congress of the International BioIron Society (IBIS), 2013-04-13 - 2013-04-17, London.

This list was generated on Tue Jul 22 23:49:40 2014 IST.