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Items by Frost, Prof Christopher

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Book Sections

Reynolds, W. and Frost, C., 2013. Coupling reactions in continuous-flow systems. In: Molnar, A., ed. Palladium-Catalysed Coupling Reactions. Weinheim: Wiley-VCH, pp. 409-440.

Frost, C.G., 1991. Palladium catalysed coupling reactions. In: Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds. Vol. 5. 2 ed. , pp. 315-350.

Articles

Reynolds, W., Plucinski, P. and Frost, C. G., 2014. Robust and reusable supported palladium catalysts for cross-coupling reactions in flow. Catalysis Science and Technology, 4 (4), pp. 948-954.

Goggins, S., Rosevere, E., Bellini, C., Allen, J. C., Marsh, B. J., Mahon, M. F. and Frost, C. G., 2014. Silyl-protected dioxaborinanes : Application in the Suzuki cross-coupling reaction. Organic and Biomolecular Chemistry, 12 (1), pp. 47-52.

Reynolds, W. R., Liu, P. M., Kociok-Kohn, G. and Frost, C. G., 2013. Sequential chelation-assisted aromatic C–H functionalisation via catalytic meta sulfonation. Synlett, 24 (20), ST-2013-D0836-L.

Liu, P. M. and Frost, C. G., 2013. Ruthenium-catalyzed C-H functionalization of arylpyrazoles : Regioselective acylation with acid chlorides. Organic Letters, 15 (22), pp. 5862-5865.

Ferreira, P.M.T., Monteiro, L.S., Pereira, G., Castanheira, E.M.S. and Frost, C.G., 2013. Synthesis of fluorescent alanines by a rhodium-catalysed conjugate addition of arylboronic acids to dehydroalanine derivatives. European Journal of Organic Chemistry

Lawrence, K., Flower, S.E., Kociok-Kohn, G., Frost, C.G. and James, T.D., 2012. A simple and effective colorimetric technique for the detection of boronic acids and their derivatives. Analytical Methods, 4 (8), pp. 2215-2217.

Allen, J. C., Kociok-Kohn, G. and Frost, C. G., 2012. Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones. Organic and Biomolecular Chemistry, 10 (1), pp. 32-35.

Saidi, O., Marafie, J., Ledger, A. E. W., Liu, P. M., Mahon, M. F., Kociok-Kohn, G., Whittlesey, M. K. and Frost, C. G., 2011. Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines. Journal of the American Chemical Society, 133 (48), pp. 19298-19301.

Burrows, A. D., Frost, C. G., Kandiah, M., Keenan, L. L., Mahon, M. F., Savarese, T. L. and Warren, J. E., 2011. The effect of reaction conditions on the nature of cadmium 1,3,5-benzenetricarboxylate metal-organic frameworks. Inorganica Chimica Acta, 366 (1), pp. 303-309.

Hargrave, J. D., Bish, G., Kociok-Kohn, G. and Frost, C. G., 2010. Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives. Organic and Biomolecular Chemistry, 8 (22), pp. 5120-5125.

Frost, C. G., Edwards, H. J., Penrose, S. D. and Gleave, R., 2010. Exploring rhodium-catalysed conjugate addition of chiral alkenylboronates using chiral olefin ligands. Synthesis, 2010 (19), pp. 3243-3247.

Frost, C. G. and Mutton, L., 2010. Heterogeneous catalytic synthesis using microreactor technology. Green Chemistry, 12 (10), pp. 1687-1703.

White, J. R., Price, G. J., Schiffers, S., Raithby, P. R., Plucinski, P. K. and Frost, C. G., 2010. A modular approach to catalytic synthesis using a dual-functional linker for Click and Suzuki coupling reactions. Tetrahedron Letters, 51 (30), pp. 3913-3917.

Burrows, A. D., Frost, C. G., Mahon, M. F., Raithby, P. R., Renouf, C. L., Richardson, C. and Stevenson, A., 2010. Dipyridyl β-diketonate complexes: versatile polydentate metalloligands for metal-organic frameworks and hydrogen-bonded networks. Chemical Communications, 46 (28), pp. 5067-5069.

Burrows, A. D., Frost, C. G., Mahon, M. F., Raithby, P. R., Richardson, C. and Stevenson, A., 2010. Solid state interconversion of cages and coordination networks via conformational change of a semi-rigid ligand. Chemical Communications, 46 (28), pp. 5064-5066.

Hargrave, J. D., Frost, C. G. and Allen, J. C., 2010. First catalytic enantioselective Dieckmann-type annulation. Synthesis, 2010 (11), A50-A52.

Edwards, H. J., Hargrave, J. D., Penrose, S. D. and Frost, C. G., 2010. Synthetic applications of rhodium catalysed conjugate addition. Chemical Society Reviews, 39 (6), pp. 2093-2105.

Hargrave, J.D., Allen, J.C. and Frost, C.G., 2010. Alternatives to organoboron reagents in rhodium-catalyzed conjugate additions. Chemistry - An Asian Journal, 5 (3), pp. 386-396.

Hargrave, J. D., Allen, J. C., Kociok-Kohn, G., Bish, G. and Frost, C. G., 2010. Catalytic enantioselective Dieckmann-type annulation: Synthesis of pyrrolidines with quaternary stereogenic centers. Angewandte Chemie-International Edition, 49 (10), pp. 1825-1829.

White, J.R., Price, G.J., Plucinski, P.K. and Frost, C.G., 2009. The rhodium-catalysed 1,2-addition of arylboronic acids to aldehydes and ketones with sulfonated S-Phos. Tetrahedron Letters, 50 (52), pp. 7365-7368.

Laska, U., Frost, C. G., Price, G. J. and Plucinski, P. K., 2009. Easy-separable magnetic nanoparticle-supported Pd catalysts: Kinetics, stability and catalyst re-use. Journal of Catalysis, 268 (2), pp. 318-328.

Burrows, A. D., Frost, C. G., Mahon, M. F. and Richardson, C., 2009. Sulfur-tagged metal–organic frameworks and their post-synthetic oxidation. Chemical Communications, 28, pp. 4218-4220.

Zoute, L., Kociok-Kohn, G. and Frost, C. G., 2009. Rhodium-catalyzed 1,4-additions to enantiopure acceptors: asymmetric synthesis of functionalized pyrrolizidinones. Organic Letters, 11 (12), pp. 2491-2494.

Frost, C. G., Penrose, S. D. and Gleave, R., 2009. A Practical Synthesis of α-Substituted tert-Butyl Acrylates from Meldrum's Acid and Aldehydes. Synthesis, 4, pp. 627-635.

Frost, C. G. and Hartley, B. C., 2009. Lewis Base-Promoted Hydrosilylation of Cyclic Malonates: Synthesis of β-Substituted Aldehydes and γ-Substituted Amines. The Journal of Organic Chemistry, 74 (9), pp. 3599-3602.

Burrows, A. D., Frost, C. G., Mahon, M. F. and Richardson, C., 2008. Post-synthetic modification of tagged metal-organic frameworks. Angewandte Chemie-International Edition, 47 (44), pp. 8482-8486.

Nôtre, J.L. and Frost, C.G., 2008. Rhodium-catalysed 1,4-addition-halogenation : the crucial role of lithium halide. Tetrahedron Letters, 49 (43), pp. 6217-6219.

Kruck, M., Munoz, M.P., Bishop, H.L., Butts, C.P., Lloyd-Jones, G.C., Frost, C.G., Chapman, C.J. and Kociok-Kohn, G., 2008. BINOL-3,3′-triflone N,N-dimethyl phosphoramidites : Through-space 19F31P spin-spin coupling with a remarkable dependency on temperature and solvent internal pressure. Chemistry - A European Journal, 14 (26), pp. 7808-7812.

Le Nôtre, J., Allen, J. C. and Frost, C. G., 2008. Enantioselective rhodium-catalysed 1,4-additions of 2-heteroarylzinc donors using Me-DUPHOS. Chemical Communications, 2008 (32), pp. 3795-3797.

Laska, U., Frost, C. G., Plucinski, P. K. and Price, G. J., 2008. Rhodium containing magnetic nanoparticles: effective catalysts for hydrogenation and the 1,4-addition of boronic acids. Catalysis Letters, 122 (1-2), pp. 68-75.

Chapman, C. J., Hargrave, J. D., Bish, G. and Frost, C. G., 2008. Peptide modification through site-selective residue interconversion: application of the rhodium-catalysed 1,4-addition of aryl siloxanes and boronates. Tetrahedron, 64 (40), pp. 9528-9539.

Frost, C., Penrose, S. and Gleave, R., 2008. Rhodium catalysed conjugate addition of a chiral alkenyltrifluoroborate salt: The enantioselective synthesis of hermitamides A and B. Organic and Biomolecular Chemistry, 6 (23), pp. 4340-4347.

Burrows, A. D., Frost, C. G., Mahon, M. F., Winsper, M., Richardson, C., Attfield, J. P. and Rodgers, J. A., 2008. Subtle structural variation in copper metal-organic frameworks: Syntheses, structures, magnetic properties and catalytic behaviour. Dalton Transactions, 2008 (47), pp. 6788-6795.

Tsoligkas, A.N., Simmons, M.J.H., Wood, J. and Frost, C.G., 2007. Kinetic and selectivity studies of gas-liquid reaction under Taylor flow in a circular capillary. Catalysis Today, 128 (1-2), pp. 36-46.

Frost, C.G. and Hartley, B.C., 2007. Tandem molybdenum catalyzed hydrosilylations : An expedient synthesis of β-aryl aldehydes. Organic Letters, 9 (21), pp. 4259-4261.

Le Nôtre, J., Van Mele, D. and Frost, C.G., 2007. A new method for constructing quaternary carbon centres : Tandem rhodium-catalysed 1,4-addition/intramolecular cyclisation. Advanced Synthesis & Catalysis, 349 (3), pp. 432-440.

Chapman, C.J. and Frost, C.G., 2007. Tandem and domino catalytic strategies for enantioselective synthesis. Synthesis, 2007 (1), pp. 1-21.

Laska, U., Frost, C. G., Plucinski, P. K. and Price, G. J., 2007. Easily recyclable homogeneous catalysts based on magnetic fluids. Récents Progrès en Génie des Procédés, 94, pp. 1-8.

Frost, C. G., Penrose, S. D., Lambshead, K., Raithby, P. R., Warren, J. E. and GleaveO, R., 2007. Rhodium-catalyzed conjugate addition-enantioselective protonation: The synthesis of alpha,alpha'-dibenzyl esters. Organic Letters, 9 (11), pp. 2119-2122.

Chapman, C.J., Frost, C.G., Matsuno, A. and Willis, M. C., 2007. Site-selective modification of peptides using rhodium and palladium catalysis : Complementary electrophilic and nucleophilic arylation. Chemical Communications, 2007 (38), pp. 3903-3905.

Merle, N., Frost, C.G., Kociok-Kohn, G., Willis, M. C. and Weller, A.S., 2006. Chelating phosphane-boranes as hemilabile ligands - Synthesis of [Mn(CO)3(η2-H3B·dppin)][BArF4 ] and [Mn(CO)4(η1-H3B· dppm)][BArF4]. European Journal of Inorganic Chemistry, 2006 (20), pp. 4068-4073.

Banks, J. C., Van Mele, D. and Frost, C.G., 2006. The α-arylation of α-bromo- and α-chloroenones using palladium-catalysed cross-coupling. Tetrahedron Letters, 47 (17), pp. 2863-2866.

Krakowski, M., Frost, C.G., Hartley, J.P. and Chauhan, K.K., 2006. Indium triflate catalysed Ene and Friedel Crafts additions to α-imino esters : A one-pot synthesis of α-amino acid derivatives. Letters in Organic Chemistry, 3 (3), pp. 228-230.

Douglas, T.M., Le Notre, J., Brayshaw, S.K., Frost, C.G. and Weller, A.S., 2006. Phosphine-olefin ligands : A facile dehydrogenative route to catalytically active rhodium complexes. Chemical Communications, 2006 (32), pp. 3408-3410.

Hargrave, J.D., Herbert, J., Bish, G. and Frost, C.G., 2006. Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters. Organic and Biomolecular Chemistry, 4 (17), pp. 3235-3241.

Chapman, C. J., Frost, C. G. and Mahon, M. F., 2006. Structure and reactivity of new phosphine ligands containing the hemi-labile sulfone moiety. Dalton Transactions, 2006 (18), pp. 2251-2262.

Hargrave, J.D., Frost, C.G. and Bish, G., 2006. Switching stereoselectivity in rhodium-catalysed 1,4-additions : The asymmetric synthesis of 2-substituted pyrrolizidinones. Chemical Communications, 2006 (42), pp. 4389-4391.

Merle, N., Frost, C.G., Kociok-Kohn, G., Willis, M. C. and Weller, A.S., 2005. Ruthenium (II) complexes of the chelating phosphine borane H2ClB · dppm. Journal of Organometallic Chemistry, 690 (11), pp. 2829-2834.

Hillier, S. C., Flower, S. E., Frost, C. G., Jenkins, A. T. A., Keay, R., Braven, H. and Clarkson, J., 2004. An electrochemical gene detection assay utilising T7 exonuclease activity on complementary probe-target oligonucleotide sequences. Electrochemistry Communications, 6 (12), pp. 1227-1232.

Moss, R. J., Wadsworth, K. J., Chapman, C.J. and Frost, C.G., 2004. Rhodium catalysed tandem conjugate addition-protonation : An enantioselective synthesis of 2-substituted succinic esters. Chemical Communications, 10 (17), pp. 1984-1985.

Wadsworth, K.J., Wood, F.K., Chapman, C.J. and Frost, C.G., 2004. Rhodium-catalysed 1,4-additions in water : Synthesis of succinic esters and β2-amino acid derivatives. Synlett, 2004 (11), pp. 2022-2024.

Hillier, S. C., Frost, C. G., Jenkins, A. T. A., Braven, H. T., Keay, R. W., Flower, S. E. and Clarkson, J. M., 2004. An electrochemical study of enzymatic oligonucleotide digestion. Bioelectrochemistry, 63 (1-2), pp. 307-310.

Cotgreave, J.H., Colclough, D., Kociok-Kohn, G., Ruggiero, G., Frost, C.G. and Weller, A.S., 2004. Well-defined indium(III) N-heterocyclic carbene complexes with triflate ligands : Structural models for the In(OTf)3 catalyst. Dalton Transactions, 2004 (10), pp. 1519-1520.

Merle, N., Kociok-Kohn, G., Mahon, M. F., Frost, C. G., Ruggerio, G. D., Weller, A. S. and Willis, M. C., 2004. Transition metal complexes of the chelating phosphine borane ligand Ph2PCH2Ph2P·BH3. Dalton Transactions, 2004 (22), pp. 3883-3892.

Chapman, C.J., Wadsworth, K.J. and Frost, C.G., 2003. Enantioselective rhodium-catalysed addition of boronic acids using C-symmetric aryl diphosphite ligands. Journal of Organometallic Chemistry, 680 (1-2), pp. 206-211.

Chapman, C. J., Frost, C. G., Gill-Carey, M. P., Kociok-Kohn, G., Mahon, M. F., Weller, A. S. and Willis, M. C., 2003. Diphosphine mono-sulfides: readily available chiral monophosphines. Tetrahedron: Asymmetry, 14 (6), pp. 705-710.

Chapman, C.J. and Frost, C.G., 2003. Synthesis of functionalised phenylalanines using rhodium catalysis in water. Advanced Synthesis & Catalysis, 345 (3), pp. 353-355.

Frost, C.G., Hartley, J.P. and Griffin, D., 2002. Counterion effects in indium-catalysed aromatic electrophilic substitution reactions. Tetrahedron Letters, 43 (27), pp. 4789-4791.

Frost, C.G., Hartley, J.P. and Griffin, D., 2002. Catalytic arylation of sulfamoyl chlorides : A practical synthesis of sulfonamides. Synlett, 2002 (11), pp. 1928-1930.

Patmore, N. J., Hague, C., Cotgreave, J. H., Mahon, M. F., Frost, C. G. and Weller, A. S., 2002. Silver phosphanes partnered with carborane monoanions: Synthesis, structures and use as highly active lewis acid catalysts in a hetero-Diels-Alder reaction. Chemistry - A European Journal, 8 (9), pp. 2088-2098.

Frost, C.G. and Wadsworth, K.J., 2001. Rhodium catalysed addition of boronic acids to anhydrides : A new method for the synthesis of ketones. Chemical Communications, 2001 (22), pp. 2316-2317.

Ingleson, M., Patmore, N. J., Ruggiero, G. D., Frost, C. G., Mahon, M. F., Willis, M. C. and Weller, A. S., 2001. Chelating monoborane phosphines: Rational and high-yield synthesis of [(COD)Rh{(eta(2)-BH3)Ph2PCH2PPh2}][PF6] (COD=1,5-cyclooctadiene). Organometallics, 20 (21), pp. 4434-4436.

Moreau, C., Hague, C., Weller, A.S. and Frost, C.G., 2001. Rhodium-catalysed aryl transfer to aldehydes : Counterion effects with nitrogen containing ligands. Tetrahedron Letters, 42 (39), pp. 6957-6960.

Chapman, C.J., Frost, C.G., Hartley, J.P. and Whittle, A.J., 2001. Efficient aromatic and heteroatom acylations using catalytic indium complexes with lithium perchlorate. Tetrahedron Letters, 42 (5), pp. 773-775.

Frost, C.G., Hartley, J.P. and Whittle, A.J., 2001. Indium-catalysed aryl and alkyl sulfonylation of aromatics. Synlett, 2001 (6), pp. 830-832.

Frost, C.G. and Willis, M.C., 2001. Organic aspects of organometallic chemistry. Organometallic Chemistry, 29, pp. 170-206.

Hague, C., Patmore, N. J., Frost, C. G., Mahon, M. F. and Weller, A. S., 2001. [(PPh3)Ag(CB11H6Y6)] (Y = H, Br): highly active, selective and recyclable Lewis acids for a hetero-Diels-Alder reaction. Chemical Communications, 2001 (21), pp. 2286-2287.

Chauhan, K.K. and Frost, C.G., 2000. Advances in indium-catalysed organic synthesis. Journal of the Chemical Society, Perkin Transactions 1, 2000 (18), pp. 3015-3019.

Bhandari, S., Frost, C.G., Hague, C.E., Mahon, M.F. and Molloy, K., 2000. Synthesis of functionalised (triorganostannyl)tetrazoles : supramolecular structures of n-[2-(triorganostannyl)tetrazol-5-yl]pyridine (n = 2, 3 or 4). Journal of the Chemical Society-Dalton Transactions, 2000 (5), pp. 663-669.

Moreau, C., Frost, C.G. and Murrer, B., 1999. Catalytic asymmetric hydrosilylation of ketones using mixed-ligand ruthenium complexes. Tetrahedron Letters, 40 (30), pp. 5617-5620.

Ali, T., Chauhan, K.K. and Frost, C.G., 1999. Indium triflate : an efficient catalyst for hetero Diels-Alder reactions. Tetrahedron Letters, 40 (30), pp. 5621-5624.

Frost, C.G. and Mendonça, P., 1999. Palladium catalysed mono-N-arylation of enantiopure diamines. Tetrahedron: Asymmetry, 10 (10), pp. 1831-1834.

Magnus, P., Westwood, N., Spyvee, M., Frost, C., Linnane, P., Tavares, F. and Lynch, V., 1999. Taxane diterpenes 5 : Synthesis of the A- and C-rings: An unusual rearrangement of an N-hydroxyimino lactone. Tetrahedron, 55 (21), pp. 6435-6452.

Chauhan, K.K., Frost, C.G., Love, I. and Waite, D., 1999. Indium triflate : An efficient catalyst for acylation reactions. Synlett, 1999 (11), pp. 1743-1744.

Frost, C.G. and Mendonça, P., 1998. Recent developments in aromatic heteroatom coupling reactions. Journal of the Chemical Society - Perkin Transcriptions 1, 1998 (16), pp. 2615-2623.

Frost, C.G. and Mendonça, P., 1997. Iterative amination strategy in the synthesis of peptidomimetics. Chemistry Letters, 26 (11), pp. 1159-1160.

Frost, C., Linnane, P., Magnus, P. and Spyvee, M., 1996. Concise synthesis of taxol A-ring components : Remote diastereoselective additions of alkenyl lithiums to aldehydes. Tetrahedron Letters, 37 (51), pp. 9139-9142.

Bauta, W.E., Booth, J., Bos, M.E., DeLuca, M., Diorazio, L., Donohoe, T.J., Frost, C., Magnus, N., Magnus, P., Mendoza, J., Pye, P., Tarrant, J.G., Thom, S. and Ujjainwalla, F., 1996. Taxane diterpenes 1. Control of relative and absolute stereochemistry in intramolecular pyrylium ylide-alkene cyclizations for the synthesis of taxol precursors. Tetrahedron, 52 (45), pp. 14081-14102.

Frost, C.G. and Williams, J. M. J., 1995. Catalytic applications of transition metals in organic synthesis. Contemporary Organic Synthesis, 2 (2), pp. 65-83.

Allen, J.V., Dawson, G.J., Frost, C.G., Williams, J. M. J. and Coote, S.J., 1994. Preparation of novel sulfur and phosphorus containing oxazolines as ligands for asymmetric catalysis. Tetrahedron, 50 (3), pp. 799-808.

Allen, J.V., Coote, S.J., Dawson, G.J., Frost, C.G., Martin, C.J. and Williams, J. M. J., 1994. Palladium-catalysed asymmetric allylic substitution : A ligand design incorporating steric and electronic effects. Journal of the Chemical Society: Perkin Transactions 1, 1994 (15), pp. 2065-2072.

Dawson, G.J., Frost, C.G., Martin, C.J., Williams, J. M. J. and Coote, S.J., 1993. Sulfides tethered to oxazolines : Ligands for enantioselective catalysis. Tetrahedron Letters, 34 (48), pp. 7793-7796.

Frost, C.G. and Williams, J. M. J., 1993. Enantioselective palladium catalysed allylic substitution with sulfur-containing oxazoline ligands. Tetrahedron: Asymmetry, 4 (8), pp. 1785-1788.

Dawson, G.J., Frost, C.G., Williams, J. M. J. and Coote, S.J., 1993. Asymmetric palladium catalyzed allylic substitution using phosphorus containing oxazoline ligands. Tetrahedron Letters, 34 (19), pp. 3149-3150.

Frost, C.G. and Williams, J. M. J., 1993. Enantioselective palladium catalysed allylic substitution with thienyl oxazoline ligands. Tetrahedron Letters, 34 (12), pp. 2015-2018.

Allen, J.V., Frost, C.G. and Williams, J. M. J., 1993. Asymmetric addition of diethylzinc to aromatic aldehydes using enantiomerically pure hydroxymethyl oxazoline ligands. Tetrahedron: Asymmetry, 4 (4), pp. 649-650.

Frost, C.G., Howarth, J. and Williams, J. M. J., 1992. Selectivity in palladium catalysed allylic substitution. Tetrahedron: Asymmetry, 3 (9), pp. 1089-1122.

Conference or Workshop Items

Yang, Z., Jolly, P., Goggins, S., Kasprzyk-Hordern, B., Frost, C. G. and Estrela, P., 2014. A novel method of aptamer immobilization for sensitive cancer biomarker detection. In: Sensors in Medicine 2014, 2014-03-25 - 2014-03-26, London.

Patent

Flower, S., Frost, C., Marsh, B. and Sharp, J., 2012. Novel Ferrocene Labels For Electrochemical Assay and Their Use in Analytical Methods. C07F 17/02(2006.01)-WO 2012/085591 A1, 28 June 2012.

This list was generated on Wed Oct 22 20:20:10 2014 IST.