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Items by Hurst, Laurence

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Number of items: 130.

Articles

Wang, J., Xie, G., Singh, M., Ghanbarian, A. T., Raskó, T., Szvetnik, A., Cai, H., Besser, D., Prigione, A., Fuchs, N. V., Schumann, G. G., Chen, W., Lorincz, M. C., Ivics, Z., Hurst, L. D. and Izsvák, Z., 2014. Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells. Nature, 516, pp. 405-409.

Yin, S., Yang, J., Lin, B., Deng, W., Zhang, Y., Yi, X., Shi, Y., Tao, Y., Cai, J., Wu, C.-I., Zhao, G., Hurst, L.D., Zhang, J., Hu, L. and Kong, X., 2014. Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients. Scientific Reports, 4, 6036.

Laabei, M., Recker, M., Rudkin, J. K., Aldeljawi, M., Gulay, Z., Sloan, T. J., Williams, P., Endres, J. L., Bayles, K. W., Fey, P. D., Yajjala, V. K., Widhelm, T., Hawkins, E., Lewis, K., Parfett, S., Scowen, L., Peacock, S. J., Holden, M., Wilson, D., Read, T. D., Van Den Elsen, J., Priest, N. K., Feil, E. J., Hurst, L. D., Josefsson, E. and Massey, R. C., 2014. Predicting the virulence of MRSA from its genome sequence. Genome Research, 24 (5), pp. 839-849.

Sealey, K. L., Harris, S. R., Fry, N. K., Hurst, L. D., Gorringe, A. R., Parkhill, J. and Preston, A., 2014. Forthcoming. Genomic analysis of isolates from the UK 2012 pertussis outbreak reveals that vaccine antigen genes are unusually fast evolving. Journal of Infectious Diseases Item availability may be restricted.

Maharjan, R., Nilsson, S., Sung, J., Haynes, K., Beardmore, R.E., Hurst, L.D., Ferenci, T. and Gudelj, I., 2013. The form of a trade-off determines the response to competition. Ecology Letters, 16 (10), pp. 1267-1276.

Woods, S., Coghlan, A., Rivers, D., Warnecke, T., Jeffries, S. J., Kwon, T., Rogers, A., Hurst, L. and Ahringer, J., 2013. Duplication and retention biases of essential and non-essential genes revealed by systematic knockdown analyses. Plos Genetics, 9 (5), e1003330.

Yang, S., Yuan, Y., Wang, L., Li, J., Wang, W., Liu, H., Chen, J.-q., Hurst, L. D. and Tian, D., 2012. Great majority of recombination events in Arabidopsis are gene conversion events. Proceedings of the National Academy of Sciences of the United States of America, 109 (51), pp. 20992-20997.

Feher, T., Bogos, B., Mehi, O., Fekete, G., Csorgo, B., Kovacs, K., Posfai, G., Papp, B., Hurst, L. D. and Pal, C., 2012. Competition between transposable elements and mutator genes in bacteria. Molecular Biology and Evolution, 29 (10), pp. 3153-3159.

He, C., Li, Z., Chen, P., Huang, H., Hurst, L. D. and Chen, J., 2012. Young intragenic miRNAs are less coexpressed with host genes than old ones: Implications of miRNA-host gene coevolution. Nucleic Acids Research, 40 (9), pp. 4002-4012.

Warnecke, T. and Hurst, L. D., 2011. Error prevention and mitigation as forces in the evolution of genes and genomes. Nature Reviews Genetics, 12 (12), pp. 875-881.

Nahorski, M. S., Reiman, A., Lim, D. H. K., Nookala, R. K., Seabra, L., Lu, X. H., Fenton, J., Boora, U., Nordenskjold, M., Latif, F., Hurst, L. D. and Maher, E. R., 2011. Birt Hogg-Dube Syndrome-Associated FLCN Mutations Disrupt Protein Stability. Human Mutation, 32 (8), pp. 921-929.

Beardmore, R. E., Gudelj, I., Lipson, D. A. and Hurst, L. D., 2011. Metabolic trade-offs and the maintenance of the fittest and the flattest. Nature, 472 (7343), pp. 342-346.

Hurst, L. D., 2011. Molecular genetics: The sound of silence. Nature, 471 (7340), pp. 582-583.

Garfield, A. S., Cowley, M., Smith, F. M., Moorwood, K., Stewart-Cox, J. E., Gilroy, K., Baker, S., Xia, J., Dalley, J. W., Hurst, L. D., Wilkinson, L. S., Isles, A. R. and Ward, A., 2011. Distinct physiological and behavioural functions for parental alleles of imprinted Grb10. Nature, 469 (7331), pp. 534-538.

Zhang, Z. G., Zhou, L., Hu, L. D., Zhu, Y. F., Xu, H., Liu, Y., Chen, X. F., Yi, X. F., Kong, X. Y. and Hurst, L. D., 2010. Nonsense-mediated decay targets have multiple sequence-related features that can inhibit translation. Molecular Systems Biology, 6, 442.

MacLean, R. C., Fuentes-Hernandez, A., Greig, D., Hurst, L. D. and Gudelj, I., 2010. A mixture of "cheats" and "co-operators" can enable maximal group benefit. PLoS Biology, 8 (9), e1000486.

Warnecke, T., Huang, Y., Przytycka, T. M. and Hurst, L. D., 2010. Unique cost dynamics elucidate the role of frameshifting errors in promoting translational robustness. Genome Biology and Evolution, 2, pp. 636-645.

Mcdonald, L. A., Gerrelli, D., Fok, Y., Hurst, L. D. and Tickle, C., 2010. Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. Journal Of Anatomy, 216 (6), pp. 683-691.

Charalambous, M., Cowley, M., Geoghegan, F., Smith, F. M., Radford, E. J., Marlow, B. P., Graham, C. F., Hurst, L. D. and Ward, A., 2010. Maternally-inherited Grb10 reduces placental size and efficiency. Developmental Biology, 337 (1), pp. 1-8.

Necsulea, A., Semon, M., Duret, L. and Hurst, L. D., 2009. Monoallelic expression and tissue specificity are associated with high crossover rates. Trends in Genetics, 25 (12), pp. 519-522.

Warnecke, T., Wang, G. Z., Lercher, M. J. and Hurst, L. D., 2009. Does negative auto-regulation increase gene duplicability? BMC Evolutionary Biology, 9, 193.

Zhang, Z. G., Xin, D. D., Wang, P., Zhou, L., Hu, L. D., Kong, X. Y. and Hurst, L. D., 2009. Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay. BMC Biology, 7 (23).

Pink, C. J., Swaminathan, S. K., Dunham, I., Rogers, J., Ward, A. and Hurst, L. D., 2009. Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates. Genome Biology and Evolution, 2009, pp. 13-22.

Hurst, L. D., 2009. Evolutionary genomics and the reach of selection. Journal of Biology, 8 (2), p. 12.

Yin, S., Wang, P., Deng, W., Zheng, H., Hu, L., Hurst, L. D. and Kong, X., 2009. Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals. Genome Biology, 10 (7), R74.

Hurst, L. D., 2009. Genetics and the understanding of selection. Nature Reviews Genetics, 10 (2), pp. 83-93.

Hurst, L., 2009. Three's a crowd. New Scientist, 203 (2725), p. 73.

Wang, P., Yin, S., Zhang, Z., Xin, D., Hu, L., Kong, X. and Hurst, L., 2008. Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes. Genome Biology, 9 (12), R169.

Forde, S. E., Beardmore, R. E., Gudelj, I., Arkin, S. S., Thompson, J. N. and Hurst, L. D., 2008. Understanding the limits to generalizability of experimental evolutionary models. Nature, 455 (7210), pp. 220-223.

Lopes, S. S., Yang, X. Y., Muller, J., Carney, T. J., McAdow, A. R., Rauch, G.-J., Jacoby, A. S., Hurst, L. D., Delfino-Machin, M., Haffter, P., Geisler, R., Johnson, S. L., Ward, A. and Kelsh, R. N., 2008. Leukocyte tyrosine kinase functions in pigment cell development. Plos Genetics, 4 (3), e1000026.

Reuter, M., Engelstadter, J., Fontanillas, P. and Hurst, L. D., 2008. A test of the null model for 5 ' UTR evolution based on GC content. Molecular Biology and Evolution, 25 (5), pp. 801-804.

de Crespigny, F. E. C., Hurst, L. D. and Wedell, N., 2008. Do Wolbachia-associated incompatibilities promote polyandry? Evolution, 62 (1), pp. 107-122.

Parmley, J. L. and Hurst, L. D., 2007. Exonic splicing regulatory elements Skew synonymous codon usage near intron-exon boundaries in mammals. Molecular Biology and Evolution, 24 (8), pp. 1600-1603.

Parmley, J. L. and Hurst, L. D., 2007. How common are intragene windows with K-A > K-S owing to purifying selection on synonymous mutations? Journal of Molecular Evolution, 64 (6), pp. 646-655.

Parmley, J. L. and Hurst, L. D., 2007. How do synonymous mutations affect fitness? Bioessays, 29 (6), pp. 515-519.

Parmley, J. L., Urrutia, A. O., Potrzebowski, L., Kaessmann, H. and Hurst, L. D., 2007. Splicing and the evolution of proteins in mammals. PLoS Biology, 5 (2), e14.

Batada, N. N., Reguly, T., Breitkreutz, A., Boucher, L., Breitkreutz, B. J., Hurst, L. D. and Tyers, M., 2007. Still stratus not altocumulus: Further evidence against the date/party hub distinction. PLoS Biology, 5 (6), pp. 1202-1206.

Poyatos, J. F. and Hurst, L. D., 2007. The determinants of gene order conservation in yeasts. Genome Biology, 8 (11).

Hurst, L. D., Feil, E. J. and Rocha, E. P. C., 2006. Causes of trends in amino-acid gain and loss. Nature, 442 (7105), E11-E12.

Pal, C., Papp, B., Lercher, M. J., Csermely, P., Oliver, S. G. and Hurst, L. D., 2006. Chance and necessity in the evolution of minimal metabolic networks. Nature, 440 (7084), pp. 667-670.

Lercher, M. J. and Hurst, L. D., 2006. Co-expressed yeast genes cluster over a long range but are not regularly spaced. Journal of Molecular Biology, 359 (3), pp. 825-831.

Rocha, E. P. C., Smith, J. M., Hurst, L. D., Holden, M. T. G., Cooper, J. E., Smith, N. H. and Feil, E. J., 2006. Comparisons of dN/dS are time dependent for closely related bacterial genomes. Journal of Theoretical Biology, 239 (2), pp. 226-235.

Parmley, J. L., Chamary, J. V. and Hurst, L. D., 2006. Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers. Molecular Biology and Evolution, 23 (2), pp. 301-309.

Batada, N. N., Hurst, L. D. and Tyers, M., 2006. Evolutionary and physiological importance of hub proteins. Plos Computational Biology, 2 (7), e88.

Chamary, J. V., Parmley, J. L. and Hurst, L. D., 2006. Hearing silence: non-neutral evolution at synonymous sites in mammals. Nature Reviews Genetics, 7 (2), pp. 98-108.

Simoes, B., Conceicao, N., Viegas, C. S. B., Pinto, J. P., Gavaia, P. J., Hurst, L. D., Kelsh, R. N. and Cancela, M. L., 2006. Identification of a promoter element within the zebrafish colX alpha 1 gene responsive to Runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2 alpha A2. Calcified Tissue International, 79 (4), pp. 230-244.

Batada, N. N., Reguly, T., Breitkreutz, A., Boucher, L., Breitkreutz, B. J., Hurst, L. D. and Tyers, M., 2006. Stratus not altocumulus: A new view of the yeast protein interaction network. PLoS Biology, 4 (10), e217.

Ruvinsky, A., Eskesen, S. T., Eskesen, F. N. and Hurst, L. D., 2005. Can codon usage bias explain intron phase distributions and exon symmetry? Journal of Molecular Evolution, 60 (1), pp. 99-104.

Gissen, P., Johnson, C. A., Gentle, D., Hurst, L. D., Doherty, A. J., O'Kane, C. J., Kelly, D. A. and Maher, E. R., 2005. Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. Human Molecular Genetics, 14 (10), pp. 1261-1270.

Hurst, L. D. and Pal, C., 2005. Dissecting dispensability. Nature Genetics, 37 (3), pp. 214-215.

Sun, M., Hurst, L. D., Carmichael, G. G. and Chen, J. J., 2005. Evidence for a preferential targeting of 3 '-UTRs by cis-encoded natural antisense transcripts. Nucleic Acids Research, 33 (17), pp. 5533-5543.

Chen, J. J., Sun, M., Hurst, L. D., Carmichael, G. G. and Rowley, J. D., 2005. Genome-wide analysis of coordinate expression and evolution of human cis-encoded sense-antisense transcripts. Trends in Genetics, 21 (6), pp. 326-329.

Chen, J. J., Sun, M., Hurst, L. D., Carmichael, G. G. and Rowley, J. D., 2005. Human antisense genes have unusually short introns: evidence for selection for rapid transcription. Trends in Genetics, 21 (4), pp. 203-207.

Pinto, J. P., Conceicao, N. M., Viegas, C. S., Leite, R. B., Hurst, L. D., Kelsh, R. N. and Cancela, M. L., 2005. Identification of a new pebp2 alpha A2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro. Journal of Bone and Mineral Research, 20 (8), pp. 1440-1453.

Holden, M. T. G., Feil, E. J., Lindsay, J. A., Peacock, S. J., Day, N. P. J., Enright, M. C., Foster, T. J., Moore, C. E., Hurst, L., Atkin, R., Barron, A., Bason, N., Bentley, S. D., Chillingworth, C., Chillingworth, T., Churcher, C., Clark, L., Corton, C., Cronin, A., Doggett, J., Dowd, L., Feltwell, T., Hance, Z., Harris, B., Hauser, H., Holroyd, S., Jagels, K., James, K. D., Lennard, N., Line, A., Mayes, R., Moule, S., Mungall, K., Ormond, D., Quail, M. A., Rabbinowitsch, E., Rutherford, K., Sanders, M., Sharp, S., Simmonds, M., Stevens, K., Whitehead, S., Barrell, B. G., Spratt, B. G. and Parkhill, J., 2004. Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance. Proceedings of the National Academy of Sciences of the United States of America, 101 (26), pp. 9786-9791.

Pal, C. and Hurst, L. D., 2004. Evidence against the selfish operon theory. Trends in Genetics, 20 (6), pp. 232-234.

Freeland, S. J. and Hurst, L. D., 2004. Evolution encoded. Scientific American, 290 (4), pp. 84-91.

Hurst, L. D., Pal, C. and Lercher, M. J., 2004. The evolutionary dynamics of eukaryotic gene order. Nature Reviews Genetics, 5 (4), pp. 299-310.

Lercher, M. J., Urrutia, A. O., Pavlicek, A. and Hurst, L. D., 2003. A unification of mosaic structures in the human genome. Human Molecular Genetics, 12 (19), pp. 2411-2415.

Lercher, M. J., Blumenthal, T. and Hurst, L. D., 2003. Coexpression of neighboring genes in Caenorhabditis elegans is mostly due to operons and duplicate genes. Genome Research, 13 (2), pp. 238-243.

Papp, B., Pal, C. and Hurst, L. D., 2003. Dosage sensitivity and the evolution of gene families in yeast. Nature, 424 (6945), pp. 194-197.

Charalambous, M., Ward, A. and Hurst, L. D., 2003. Evidence for a priming effect on maternal resource allocation: implications for interbrood competition. Proceedings of the Royal Society B: Biological Sciences, 270, S100-S103.

Pal, C. and Hurst, L. D., 2003. Evidence for co-evolution of gene order and recombination rate. Nature Genetics, 33 (3), pp. 392-395.

Lercher, M. J., Urrutia, A. O. and Hurst, L. D., 2003. Evidence that the human X chromosome is enriched for male-specific but not female-specific genes. Molecular Biology and Evolution, 20 (7), pp. 1113-1116.

Papp, B., Pal, C. and Hurst, L. D., 2003. Evolution of cis-regulatory elements in duplicated genes of yeast. Trends in Genetics, 19 (8), pp. 417-422.

Pal, C., Papp, B. and Hurst, L. D., 2003. Rate of evolution and gene dispensability. Nature, 421 (6922), pp. 496-497.

Lercher, M. J. and Hurst, L. D., 2002. Human SNP variability and mutation rate are higher in regions of high recombination. Trends in Genetics, 18 (7), pp. 337-340.

Williams, E. J. B. and Hurst, L. D., 2002. Is the synonymous substitution rate in mammals gene-specific? Molecular Biology and Evolution, 19 (8), pp. 1395-1398.

Hurst, L. D. and Ellegren, H., 2002. Mystery of the mutagenic male. Nature, 420 (6914), pp. 365-366.

Hurst, L. D., Williams, E. J. B. and Pal, C., 2002. Natural selection promotes the conservation of linkage of co-expressed genes. Trends in Genetics, 18 (12), pp. 604-606.

Hurst, L. D. and Randerson, J. P., 2002. Parasitic sex puppeteers. Scientific American, 286 (4), pp. 56-61.

Randerson, J. P. and Hurst, L. D., 2002. Survival and anisogamy - Response. Trends in Ecology & Evolution, 17 (8), p. 358.

Hurst, L. D., 2002. The Ka/Ks ratio: diagnosing the form of sequence evolution. Trends in Genetics, 18 (9), pp. 486-487.

Lercher, M. J., Smith, N. G. C., Eyre-Walker, A. and Hurst, L. D., 2002. The evolution of isochores: Evidence from SNP frequency distributions. Genetics, 162 (4), pp. 1805-1810.

Randerson, J. P. and Hurst, L. D., 2001. A comparative test of a theory for the evolution of anisogamy. Proceedings of the Royal Society B: Biological Sciences, 268 (1469), pp. 879-884.

Pal, C., Papp, B. and Hurst, L. D., 2001. Does the recombination rate affect the efficiency of purifying selection? The yeast genome provides a partial answer. Molecular Biology and Evolution, 18 (12), pp. 2323-2326.

Hurst, L. D. and Pal, C., 2001. Evidence for purifying selection acting on silent sites in BRCA1. Trends in Genetics, 17 (2), pp. 62-65.

Hurst, L. D., 2001. Evolutionary genomics - Sex and the X. Nature, 411 (6834), pp. 149-150.

Hurst, L. D. and Merchant, A. R., 2001. High guanine-cytosine content is not an adaptation to high temperature: a comparative analysis amongst prokaryotes. Proceedings of the Royal Society B: Biological Sciences, 268 (1466), pp. 493-497.

Pal, C., Papp, B. and Hurst, L. D., 2001. Highly expressed genes in yeast evolve slowly. Genetics, 158 (2), pp. 927-931.

Eyre-Walker, A. and Hurst, L. D., 2001. The evolution of isochores. Nature Reviews Genetics, 2 (7), pp. 549-555.

Randerson, J. P. and Hurst, L. D., 2001. The uncertain evolution of the sexes. Trends in Ecology & Evolution, 16 (10), pp. 571-579.

Williams, E. J. B. and Hurst, L. D., 2000. The proteins of linked genes evolve at similar rates. Nature, 407 (6806), pp. 900-903.

This list was generated on Tue Jun 30 01:48:26 2015 IST.