Items by Leak, David

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Number of items: 46.

Book Sections

Patterson, E. and Leak, D., 2014. Enzyme biotransformations and reactors. In: Patterson, D., Letcher, T. and Scott, J., eds. Chemical Processes for a Sustainable Future. Royal Society of Chemistry.


Aw, R., Barton, G. R. and Leak, D. J., 2017. Insights into the prevalence and underlying causes of clonal variation through transcriptomic analysis in Pichia pastoris. Applied Microbiology and Biotechnology, 101 (12), pp. 5045-5058.

Ward, D. P., Hewitson, P., Cárdenas-Fernández, M., Hamley-Bennett, C., Díaz-Rodríguez, A., Douillet, N., Adams, J. P., Leak, D. J., Ignatova, S. and Lye, G. J., 2017. Centrifugal partition chromatography in a biorefinery context:Optimisation and scale-up of monosaccharide fractionation from hydrolysed sugar beet pulp. Journal of Chromatography A, 1497, pp. 56-63.

Cárdenas-Fernández, M., Bawn, M., Hamley-Bennett, C., Bharat, P. K. V., Subrizi, F., Suhaili, N., Ward, D. P., Bourdin, S., Dalby, P. A., Hailes, H. C., Hewitson, P., Ignatova, S., Kontoravdi, C., Leak, D. J., Shah, N., Sheppard, T. D., Ward, J. M. and Lye, G. J., 2017. An integrated biorefinery concept for conversion of sugar beet pulp into value-added chemicals and pharmaceutical intermediates. Faraday Discussions

Tredwell, G. D., Aw, R., Edwards-Jones, B., Leak, D. J. and Bundy, J. G., 2017. Rapid screening of cellular stress responses in recombinant Pichia pastoris strains using metabolite profiling. Journal of Industrial Microbiology and Biotechnology, 44 (3), pp. 413-417.

Elbehery, A. H. A., Leak, D. J. and Siam, R., 2017. Novel thermostable antibiotic resistance enzymes from the Atlantis II Deep Red Sea brine pool. Microbial Biotechnology, 10 (1), pp. 189-202.

Buddrus, L., Andrews, E. S. V., Leak, D. J., Danson, M. J., Arcus, V. L. and Crennell, S. J., 2016. Crystal structure of pyruvate decarboxylase from Zymobacter palmae. Acta Crystallographica Section F:Structural Biology Communications, 72 (9), pp. 700-706.

Reeve, B., Martinez-Klimova, E., de Jonghe, J., Leak, D. J. and Ellis, T., 2016. The Geobacillus Plasmid Set:A Modular Toolkit for Thermophile Engineering. ACS Synthetic Biology

Liberal, R., Lisowska, B. K., Leak, D. J. and Pinney, J. W., 2015. PathwayBooster:a tool to support the curation of metabolic pathways. BMC Bioinformatics, 16, 86.

Todri, E., Amenaghawon, A. N., Del Val, I. J., Leak, D. J., Kontoravdi, C., Kucherenko, S. and Shah, N., 2014. Global sensitivity analysis and meta-modeling of an ethanol production process. Chemical Engineering Science, 114, pp. 114-127.

Xiao, Y., Liu, T.-T., Dai, H., Zhang, J.-J., Liu, H., Tang, H., Leak, D. J. and Zhou, N.-Y., 2012. OnpA, an unusual flavin-dependent monooxygenase containing a cytochrome b5 domain. Journal of Bacteriology, 194 (6), pp. 1342-1349.

Tredwell, G. D., Edwards-Jones, B., Leak, D. J. and Bundy, J. G., 2011. The development of metabolomic sampling procedures for Pichia pastoris, and baseline metabolome data. PLoS ONE, 6 (1), e16286.

Taylor, M. P., Van Zyl, L., Tuffin, I. M., Leak, D. J. and Cowan, D. A., 2011. Genetic tool development underpins recent advances in thermophilic whole-cell biocatalysts:Recent advances in thermophilic genetic systems. Microbial Biotechnology, 4 (4), pp. 438-448.

Brandt, A., Ray, M. J., To, T. Q., Leak, D. J., Murphy, R. J. and Welton, T., 2011. Ionic liquid pretreatment of lignocellulosic biomass with ionic liquid–water mixtures. Green Chemistry, 13 (9), pp. 2489-2499.

Brandt, A., Hallett, J. P., Leak, D. J., Murphy, R. J. and Welton, T., 2010. The effect of the ionic liquid anion in the pretreatment of pine wood chips. Green Chemistry, 12 (4), pp. 672-679.

Crowhurst, N. A. and Leak, D. J., 2010. Biobutanol:A better biofuel? International Sugar Journal, 112 (1334), pp. 64-73.

Ray, M. J., Leak, D. J., Spanu, P. D. and Murphy, R. J., 2010. Brown rot fungal early stage decay mechanism as a biological pretreatment for softwood biomass in biofuel production. Biomass and Bioenergy, 34 (8), pp. 1257-1262.

Leak, D. J., 2010. Venter creates synthetic life:Should we be scared? Chemistry and Industry, 2010 (16), pp. 16-17.

Leak, D. J., Sheldon, R. A., Woodley, J. M. and Adlercreutz, P., 2009. Biocatalysts for selective introduction of oxygen. Biocatalysis and Biotransformation, 27 (1), pp. 1-26.

Jiang, X.-W., Liu, H., Xu, Y., Wang, S.-J., Leak, D. J. and Zhou, N.-Y., 2009. Genetic and biochemical analyses of chlorobenzene degradation gene clusters in Pandoraea sp. strain MCB032. Archives of Microbiology, 191 (6), pp. 485-492.

Borole, A. P., Hamilton, C. Y., Vishnivetskaya, T., Leak, D. and Andras, C., 2009. Improving power production in acetate-fed microbial fuel cells via enrichment of exoelectrogenic organisms in flow-through systems. Biochemical Engineering Journal, 48 (1), pp. 71-80.

Borole, A. P., Hamilton, C. Y., Vishnivetskaya, T. A., Leak, D., Andras, C., Morrell-Falvey, J., Keller, M. and Davison, B., 2009. Integrating engineering design improvements with exoelectrogen enrichment process to increase power output from microbial fuel cells. Journal of Power Sources, 191 (2), pp. 520-527.

Cripps, R. E., Eley, K., Leak, D. J., Rudd, B., Taylor, M., Todd, M., Boakes, S., Martin, S. and Atkinson, T., 2009. Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production. Metabolic Engineering, 11 (6), pp. 398-408.

Taylor, M. P., Esteban, C. D. and Leak, D. J., 2008. Development of a versatile shuttle vector for gene expression in Geobacillus spp. Plasmid, 60 (1), pp. 45-52.

Shen, Y., Yan, D.-Z., Chi, X.-Q., Yang, Y.-Y., Leak, D. J. and Zhou, N.-Y., 2008. Degradation of cyclohexylamine by a new isolate of Pseudomonas plecoglossicida. World Journal of Microbiology and Biotechnology, 24 (8), pp. 1623-1625.

Baptista, I.I.R., Emanuelsson, E. A. C., Peeva, L.G., Mantalaris, A., Livingston, A.G., Zhou, N.Y. and Leak, D.J., 2008. Evidence of species succession during chlorobenzene biodegradation. Biotechnology and Bioengineering, 99 (1), pp. 68-74.

Thompson, A. H., Studholme, D. J., Green, E. M. and Leak, D. J., 2008. Heterologous expression of pyruvate decarboxylase in Geobacillus thermoglucosidasius. Biotechnology Letters, 30 (8), pp. 1359-1365.

Champreda, V., Choi, Y.-J., Zhou, N. and Leak, D., 2006. Alteration of the stereo- and regioselectivity of alkene monooxygenase based on coupling protein interactions. Applied Microbiology and Biotechnology, 71 (6), pp. 840-847.

Baptista, I. I. R., Peeva, L. G., Zhou, N.-Y., Leak, D. J., Mantalaris, A. and Livingston, A. G., 2006. Stability and performance of Xanthobacter autotrophicus GJ10 during 1,2-dichloroethane biodegradation. Applied and Environmental Microbiology, 72 (6), pp. 4411-4418.

Ragauskas, A. J., Williams, C. K., Davison, B. H., Britovsek, G., Cairney, J., Eckert, C. A., Frederick, W. J., Hallett, J. P., Leak, D. J., Liotta, C. L., Mielenz, J. R., Murphy, R., Templer, R. and Tschaplinski, T., 2006. The path forward for biofuels and biomaterials. Science, 311 (5760), pp. 484-489.

Chan Kwo Chion, C. K., Askew, S. E. and Leak, D. J., 2005. Cloning, expression, and site-directed mutagenesis of the propene monooxygenase genes from Mycobacterium sp. strain M156. Applied and Environmental Microbiology, 71 (4), pp. 1909-1914.

Liu, D. Q., Liu, H., Gao, X. L., Leak, D. J. and Zhou, N. Y., 2005. Arg169 is essential for catalytic activity of 3-hydroxybenzoate 6-hydroxylase from Klebsiella pneumoniae M5a1. Microbiological Research, 160 (1), pp. 53-59.

Conference or Workshop Items

Ward, C. E. and Leak, D. J., 2013. Application of 13C metabolic flux analysis to understanding the physiology of engineered Geobacillus Thermoglucosidasius. In: Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 2013-11-03 - 2013-11-08.


Brandt, A., Hallett, J. P., Leak, D. J., Murphy, R. J. and Welton, T., 2011. Ionic liquid pretreatment of lignocellulosic biomass with ionic liquid-water mixtures P51157WO. UNSPECIFIED, 2011.

This list was generated on Mon Jun 18 20:29:26 2018 IST.