Research

Items by Leese, Mathew

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Number of items: 6.

2010

Leese, M. P., Jourdan, F., Ferrandis, E., Regis-Lydi, S., Kasprzyk, P. G., Stengel, C., Newman, S. P., Purohit, A., Reed, M. J. and Potter, B. V. L., 2010. Optimisation of tetrahydroisoquinoline based microtubule disruptors as anti-cancer agents. EJC Supplements, 8 (7), p. 141.

2006

Leese, M. P., Leblond, B., Smith, A., Newman, S. P., Di Fiore, A., De Simone, G., Supuran, C. T., Purohit, A., Reed, M. J. and Potter, B. V. L., 2006. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents : synthesis, in vitro SAR, protein crystallography, and in vivo activity. Journal of Medicinal Chemistry, 49 (26), pp. 7683-7696.

2005

Leese, M. P., Hejaz, H. A. M., Mahon, M. F., Newman, S. P., Purohit, A., Reed, M. J. and Potter, B. V. L., 2005. A-ring-substituted estrogen-3- 0 -sulfamates: potent multitargeted anticancer agents. Journal of Medicinal Chemistry, 48, pp. 5243-5256.

Purohit, A., Ghilchik, M. W., Leese, M. P., Potter, B. V. L. and Reed, M. J., 2005. Regulation of aromatase activity by cytokines, PGE2 and 2-methoxyoestrone-3-0 -sulphamate in fibroblasts derived from normal and malignant breast tissues. Steroid Biochemistry & Molecular Biology, 94 (1), pp. 167-172.

2004

Leese, M. P., Newman, S. P., Purohit, A., Reed, M. J. and Potter, B. V. L., 2004. 2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents. Bioorganic & Medicinal Chemistry Letters, 14, pp. 3135-3138.

2003

Ho, Y. T., Newman, S. P., Purohit, A., Leese, M. P., Potter, B. V. L. and Reed, M. J., 2003. The effects of 2-methyl oestrogens and their sukphamaoylated derivatives in conjunction with TNF-α on endothelial and fibroblast cell growth, morphology and apoptosis. Steroid Biochemistry & Molecular Biology, 86, pp. 189-196.

This list was generated on Thu Apr 24 17:24:25 2014 IST.