Items by Bubert, Christian

2011

Woo, L. W. L., Bubert, C., Purohit, A. and Potter, B. V. L., 2011. Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity. ACS Medicinal Chemistry Letters, 2 (3), pp. 243-247.

2008

Foster, P. A., Chander, S. K., Newman, S. P., Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Zhou, D. J., Chen, S. A., Potter, B. V. L., Reed, M. J. and Purohit, A., 2008. A new therapeutic strategy against hormone-dependent breast cancer : the preclinical development of a dual aromatase and sulfatase inhibitor. Clinical Cancer Research, 14 (20), pp. 6469-6477.

Bubert, C., Woo, L. W. L., Sutcliffe, O. B., Mahon, M. F., Chander, S. K., Purohit, A., Reed, M. J. and Potter, B. V. L., 2008. Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile : SAR, crystal structures, in vitro and in vivo activities. ChemMedChem, 3 (11), pp. 1708-1730.

Jourdan, F., Bubert, C., Leese, M. P., Smith, A., Ferrandis, E., Regis-Lydi, S., Newman, S. P., Purohit, A., Reed, M. J. and Potter, B. V. L., 2008. Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates : synthesis, in vitro evaluation and computational modelling. Organic and Biomolecular Chemistry, 6 (22), pp. 4108-4119.

2007

Woo, L. W. L., Bubert, C., Sutcliffe, O. B., Smith, A., Chander, S. K., Mahon, M. F., Purohit, A., Reed, M. J. and Potter, B. V. L., 2007. Dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry, 50 (15), pp. 3540-3560.

2006

Vicker, N., Lawrence, H. R., Allan, G. M., Bubert, C., Smith, A., Tutill, H. J., Purohit, A., Day, J. M., Mahon, M. F., Reed, M. J. and Potter, B. V. L., 2006. Focused libraries of 16-substituted estrone derivatives and modified E-ring steroids : inhibitors of 17β-hydroxysteroid dehydrogenase type 1. ChemMedChem, 1 (4), pp. 464-481.

Allan, G. M., Lawrence, H. R., Cornet, J., Bubert, C., Fischer, D. S., Vicker, N., Smith, A., Tutill, H. J., Purohit, A., Day, J. M., Mahon, M. F., Reed, M. J. and Potter, B. V. L., 2006. Modification of estrone at the 6, 16, and 17 positions : novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1. Journal of Medicinal Chemistry, 49 (4), pp. 1325-1345.

Allan, G. M., Bubert, C., Vicker, N., Smith, A., Tutill, H. J., Purohit, A., Reed, M. J. and Potter, B. V. L., 2006. Novel, potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology, 248 (1), pp. 204-207.

2003

Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Grasso, A., Chander, S., Purohit, A., Reed, M. J. and Potter, B. V. L., 2003. First dual aromatase-steroid sulfatase inhibitor. Journal of Medicinal Chemistry, 46 (15), pp. 3193-3196.