Items by Bubert, Christian
 | Up a level |
Articles
Woo, L. W. L., Bubert, C., Purohit, A. and Potter, B. V. L., 2011. Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity. ACS Medicinal Chemistry Letters, 2 (3), pp. 243-247.
Foster, P. A., Chander, S. K., Newman, S. P., Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Zhou, D. J., Chen, S. A., Potter, B. V. L., Reed, M. J. and Purohit, A., 2008. A new therapeutic strategy against hormone-dependent breast cancer : the preclinical development of a dual aromatase and sulfatase inhibitor. Clinical Cancer Research, 14 (20), pp. 6469-6477.
Bubert, C., Woo, L. W. L., Sutcliffe, O. B., Mahon, M. F., Chander, S. K., Purohit, A., Reed, M. J. and Potter, B. V. L., 2008. Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile : SAR, crystal structures, in vitro and in vivo activities. ChemMedChem, 3 (11), pp. 1708-1730.
Jourdan, F., Bubert, C., Leese, M. P., Smith, A., Ferrandis, E., Regis-Lydi, S., Newman, S. P., Purohit, A., Reed, M. J. and Potter, B. V. L., 2008. Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling. Organic and Biomolecular Chemistry, 6 (22), pp. 4108-4119.
Woo, L. W. L., Bubert, C., Sutcliffe, O. B., Smith, A., Chander, S. K., Mahon, M. F., Purohit, A., Reed, M. J. and Potter, B. V. L., 2007. Dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry, 50 (15), pp. 3540-3560.
Vicker, N., Lawrence, H. R., Allan, G. M., Bubert, C., Smith, A., Tutill, H. J., Purohit, A., Day, J. M., Mahon, M. F., Reed, M. J. and Potter, B. V. L., 2006. Focused libraries of 16-substituted estrone derivatives and modified E-ring steroids : inhibitors of 17β-hydroxysteroid dehydrogenase type 1. ChemMedChem, 1 (4), pp. 464-481.
Allan, G. M., Lawrence, H. R., Cornet, J., Bubert, C., Fischer, D. S., Vicker, N., Smith, A., Tutill, H. J., Purohit, A., Day, J. M., Mahon, M. F., Reed, M. J. and Potter, B. V. L., 2006. Modification of estrone at the 6, 16, and 17 positions : novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1. Journal of Medicinal Chemistry, 49 (4), pp. 1325-1345.
Allan, G. M., Bubert, C., Vicker, N., Smith, A., Tutill, H. J., Purohit, A., Reed, M. J. and Potter, B. V. L., 2006. Novel, potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology, 248 (1), pp. 204-207.
Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Grasso, A., Chander, S., Purohit, A., Reed, M. J. and Potter, B. V. L., 2003. First dual aromatase-steroid sulfatase inhibitor. Journal of Medicinal Chemistry, 46 (15), pp. 3193-3196.
